Paolo De Coppi

Research interests

Publications

• Clinical applications of human organoids

  Nature Medicine · 2025 · https://doi.org/10.1038/s41591-024-03489-3

• Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance

  Nature Cell Biology · 2022 · 10.1038/s41556-022-00843-w

• Local and systemic responses to SARS-CoV-2 infection in children and adults

  Nature · 2021 · 10.1038/s41586-021-04345-x

• Gastrointestinal features in children with COVID-19: an observation of varied presentation in eight children

  The Lancet Child & Adolescent Health · 2020 · 10.1016/s2352-4642(20)30165-6

• Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis

  Nature · 2020 · 10.1038/s41586-020-2712-z

• Intravital three-dimensional bioprinting

  Nature Biomedical Engineering · 2020 · 10.1038/s41551-020-0568-z

• An automated framework for localization, segmentation and super-resolution reconstruction of fetal brain MRI

  NeuroImage · 2019 · 10.1016/j.neuroimage.2019.116324

• Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture

  Nature Communications · 2019 · 10.1038/s41467-019-13605-4

• Opportunities and challenges of translational 3D bioprinting

  Nature Biomedical Engineering · 2019 · 10.1038/s41551-019-0471-7

• Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins

  Stem Cell Research & Therapy · 2019 · 10.1186/s13287-019-1213-1

• Lancet Commission: Stem cells and regenerative medicine

  The Lancet · 2017 · 10.1016/s0140-6736(17)31366-1

• The quiescent intracluster medium in the core of the Perseus cluster

  Nature · 2016 · 10.1038/nature18627

• Rapid Expansion of Human Epithelial Stem Cells Suitable for Airway Tissue Engineering

  American Journal of Respiratory and Critical Care Medicine · 2016 · 10.1164/rccm.201507-1414oc

• Decellularized human liver as a natural 3D-scaffold for liver bioengineering and transplantation

  Scientific Reports · 2015 · 10.1038/srep13079

• Discarded human kidneys as a source of ECM scaffold for kidney regeneration technologies

  Biomaterials · 2013 · https://doi.org/10.1016/j.biomaterials.2013.04.033

• Immunomodulatory effect of a decellularized skeletal muscle scaffold in a discordant xenotransplantation model

  Proceedings of the National Academy of Sciences · 2013 · https://doi.org/10.1073/pnas.1213228110

• Amniotic fluid stem cells improve survival and enhance repair of damaged intestine in necrotising enterocolitis via a COX-2 dependent mechanism

  Gut · 2013 · 10.1136/gutjnl-2012-303735

• Production and Implantation of Renal Extracellular Matrix Scaffolds From Porcine Kidneys as a Platform for Renal Bioengineering Investigations

  Annals of Surgery · 2012 · 10.1097/sla.0b013e31825a02ab

• Stem-cell-based, tissue engineered tracheal replacement in a child: a 2-year follow-up study

  The Lancet · 2012 · 10.1016/s0140-6736(12)60737-5

• A rat decellularized small bowel scaffold that preserves villus-crypt architecture for intestinal regeneration

  Biomaterials · 2012 · https://doi.org/10.1016/j.biomaterials.2012.01.012

• Tissue engineered human tracheas for in vivo implantation

  Biomaterials · 2010 · https://doi.org/10.1016/j.biomaterials.2010.08.005

• The origin of intermuscular adipose tissue and its pathophysiological implications

  American Journal of Physiology-Endocrinology and Metabolism · 2009 · 10.1152/ajpendo.00229.2009

• Isolation of amniotic stem cell lines with potential for therapy

  Nature Biotechnology · 2007 · https://doi.org/10.1038/nbt1274

• Amniotic Fluid and Bone Marrow Derived Mesenchymal Stem Cells Can be Converted to Smooth Muscle Cells in the Cryo-Injured Rat Bladder and Prevent Compensatory Hypertrophy of Surviving Smooth Muscle Cells

  The Journal of Urology · 2006 · https://doi.org/10.1016/j.juro.2006.09.103

• Principals of neovascularization for tissue engineering

  Molecular Aspects of Medicine · 2002 · 10.1016/s0098-2997(02)00008-0

Current projects

No projects listed.