Mathias Uhlén

Research interests

Publications

• Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays

  Cell · 2022 · https://doi.org/10.1016/j.cell.2022.04.003

• A single–cell type transcriptomics map of human tissues

  Science Advances · 2021 · https://doi.org/10.1126/sciadv.abh2169

• Developmental trajectory of the healthy human gut microbiota during the first 5 years of life

  Cell Host & Microbe · 2021 · https://doi.org/10.1016/j.chom.2021.02.021

• The protein expression profile of ACE2 in human tissues

  Molecular Systems Biology · 2020 · 10.15252/msb.20209610

• An atlas of the protein-coding genes in the human, pig, and mouse brain

  Science · 2020 · https://doi.org/10.1126/science.aay5947

• A genome-wide transcriptomic analysis of protein-coding genes in human blood cells

  Science · 2019 · https://doi.org/10.1126/science.aax9198

• The human secretome

  Science Signaling · 2019 · https://doi.org/10.1126/scisignal.aaz0274

• A deep proteome and transcriptome abundance atlas of 29 healthy human tissues

  Molecular Systems Biology · 2019 · 10.15252/msb.20188503

• How many human proteoforms are there?

  Nature Chemical Biology · 2018 · 10.1038/nchembio.2576

• A subcellular map of the human proteome

  Science · 2017 · https://doi.org/10.1126/science.aal3321

• A pathology atlas of the human cancer transcriptome

  Science · 2017 · https://doi.org/10.1126/science.aan2507

• Integrated Network Analysis Reveals an Association between Plasma Mannose Levels and Insulin Resistance

  Cell Metabolism · 2016 · https://doi.org/10.1016/j.cmet.2016.05.026

• A proposal for validation of antibodies

  Nature Methods · 2016 · 10.1038/nmeth.3995

• Tissue-based map of the human proteome

  Science · 2015 · https://doi.org/10.1126/science.1260419

• Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics

  Molecular & Cellular Proteomics · 2013 · https://doi.org/10.1074/mcp.m113.035600

• Defining the transcriptome and proteome in three functionally different human cell lines

  Molecular Systems Biology · 2010 · https://doi.org/10.1038/msb.2010.106

• Prediction of the human membrane proteome

  PROTEOMICS · 2010 · https://doi.org/10.1002/pmic.200900258

• Towards a knowledge-based Human Protein Atlas

  Nature Biotechnology · 2010 · https://doi.org/10.1038/nbt1210-1248

• A Genecentric Human Protein Atlas for Expression Profiles Based on Antibodies

  Molecular & Cellular Proteomics · 2008 · 10.1074/mcp.r800013-mcp200

• The Human Protein Atlas—a tool for pathology

  The Journal of Pathology · 2008 · 10.1002/path.2440

• ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome

  Nature Methods · 2006 · https://doi.org/10.1038/nmeth0107-13

• A Human Protein Atlas for Normal and Cancer Tissues Based on Antibody Proteomics

  Molecular & Cellular Proteomics · 2005 · 10.1074/mcp.m500279-mcp200

• A Sequencing Method Based on Real-Time Pyrophosphate

  Science · 1998 · 10.1126/science.281.5375.363

• Binding proteins selected from combinatorial libraries of an α-helical bacterial receptor domain

  Nature Biotechnology · 1997 · 10.1038/nbt0897-772

• Real-Time DNA Sequencing Using Detection of Pyrophosphate Release

  Analytical Biochemistry · 1996 · 10.1006/abio.1996.0432

• Crystal structure of the C2 fragment of streptococcal protein G in complex with the Fc domain of human IgG

  Structure · 1995 · https://doi.org/10.1016/s0969-2126(01)00157-5

• Direct solid phase sequencing of genomic and plasmid DNA using magnetic beads as solid support

  Nucleic Acids Research · 1989 · 10.1093/nar/17.13.4937

• A synthetic IgG-binding domain based on staphylococcal protein A

  Protein Engineering Design and Selection · 1987 · 10.1093/protein/1.2.107

Current projects

No projects listed.