Sabine Tejpar

Research interests

Publications

• Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer

  Nature Genetics · 2022 · 10.1038/s41588-022-01100-4

• Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages

  Cell Research · 2021 · 10.1038/s41422-020-00455-9

• A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling

  Cell Research · 2020 · https://doi.org/10.1038/s41422-020-0355-0

• Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer

  Nature Genetics · 2020 · https://doi.org/10.1038/s41588-020-0636-z

• Consensus molecular subtypes and the evolution of precision medicine in colorectal cancer

  Nature reviews. Cancer · 2017 · https://doi.org/10.1038/nrc.2016.126

• ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer

  JNCI Journal of the National Cancer Institute · 2017 · 10.1093/jnci/djx089

• Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study

  ˜The œLancet. Gastroenterology & hepatology · 2016 · 10.1016/s2468-1253(16)30014-0

• ESMO consensus guidelines for the management of patients with metastatic colorectal cancer

  Annals of Oncology · 2016 · https://doi.org/10.1093/annonc/mdw235

• The consensus molecular subtypes of colorectal cancer

  Nature Medicine · 2015 · https://doi.org/10.1038/nm.3967

• Managing synchronous liver metastases from colorectal cancer: A multidisciplinary international consensus

  Cancer Treatment Reviews · 2015 · 10.1016/j.ctrv.2015.06.006

• Fluorouracil, Leucovorin, and Irinotecan Plus Cetuximab Treatment and RAS Mutations in Colorectal Cancer

  Journal of Clinical Oncology · 2015 · 10.1200/jco.2014.59.4812

• Distal and proximal colon cancers differ in terms of molecular, pathological, and clinical features

  Annals of Oncology · 2014 · 10.1093/annonc/mdu275

• Molecular Markers Identify Subtypes of Stage III Colon Cancer Associated With Patient Outcomes

  Gastroenterology · 2014 · 10.1053/j.gastro.2014.09.041

• Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts

  Gut · 2013 · 10.1136/gutjnl-2012-304356

• Gene expression patterns unveil a new level of molecular heterogeneity in colorectal cancer

  The Journal of Pathology · 2013 · 10.1002/path.4212

• KRAS, BRAF, PIK3CA, and PTEN mutations: implications for targeted therapies in metastatic colorectal cancer

  The Lancet Oncology · 2010 · 10.1016/s1470-2045(10)70209-6

• Peutz–Jeghers syndrome: a systematic review and recommendations for management

  Gut · 2010 · 10.1136/gut.2009.198499

• Association of KRAS p.G13D Mutation With Outcome in Patients With Chemotherapy-Refractory Metastatic Colorectal Cancer Treated With Cetuximab

  JAMA · 2010 · 10.1001/jama.2010.1535

• Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

  The Lancet Oncology · 2010 · https://doi.org/10.1016/s1470-2045(10)70130-3

• Amphiregulin and Epiregulin mRNA Expression in Primary Tumors Predicts Outcome in Metastatic Colorectal Cancer Treated With Cetuximab

  Journal of Clinical Oncology · 2009 · 10.1200/jco.2008.21.3744

• Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer

  New England Journal of Medicine · 2009 · https://doi.org/10.1056/nejmoa0805019

• Prognostic Role of KRAS and BRAF in Stage II and III Resected Colon Cancer: Results of the Translational Study on the PETACC-3, EORTC 40993, SAKK 60-00 Trial

  Journal of Clinical Oncology · 2009 · https://doi.org/10.1200/jco.2009.23.3452

• Guidelines for the clinical management of familial adenomatous polyposis (FAP)

  Gut · 2008 · 10.1136/gut.2007.136127

• KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab

  Annals of Oncology · 2007 · 10.1093/annonc/mdm496

• A combined syndrome of juvenile polyposis and hereditary haemorrhagic telangiectasia associated with mutations in MADH4 ( SMAD4)

  The Lancet · 2004 · 10.1016/s0140-6736(04)15732-2

Current projects

No projects listed.