Roberto Salgado

Research interests

Publications

• Towards targeting the breast cancer immune microenvironment

  Nature reviews. Cancer · 2024 · 10.1038/s41568-024-00714-6

• Pembrolizumab plus chemotherapy as neoadjuvant treatment of high-risk, early-stage triple-negative breast cancer: results from the phase 1b open-label, multicohort KEYNOTE-173 study

  Annals of Oncology · 2020 · 10.1016/j.annonc.2020.01.072

• Assessment of Ki67 in Breast Cancer: Updated Recommendations From the International Ki67 in Breast Cancer Working Group

  JNCI Journal of the National Cancer Institute · 2020 · https://doi.org/10.1093/jnci/djaa201

• The 2019 World Health Organization classification of tumours of the breast

  Histopathology · 2020 · https://doi.org/10.1111/his.14091

• Tumor-Infiltrating Lymphocytes and Prognosis: A Pooled Individual Patient Analysis of Early-Stage Triple-Negative Breast Cancers

  Journal of Clinical Oncology · 2019 · 10.1200/jco.18.01010

• Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers

  Journal of Clinical Investigation · 2019 · 10.1172/jci96313

• Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial

  Nature Medicine · 2019 · https://doi.org/10.1038/s41591-019-0432-4

• SETER/PR: a robust 18-gene predictor for sensitivity to endocrine therapy for metastatic breast cancer

  npj Breast Cancer · 2019 · 10.1038/s41523-019-0111-0

• Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis

  Nature Medicine · 2018 · https://doi.org/10.1038/s41591-018-0078-7

• Safety and Antitumor Activity of Pembrolizumab in Patients with Estrogen Receptor–Positive/Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer

  Clinical Cancer Research · 2018 · 10.1158/1078-0432.ccr-17-3452

• Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non–Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourinary Carcinomas, and Primary Brain Tumors

  Advances in Anatomic Pathology · 2017 · 10.1097/pap.0000000000000161

• Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis

  The Lancet Oncology · 2017 · 10.1016/s1470-2045(17)30516-8

• Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non–Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourina

  Advances in Anatomic Pathology · 2017 · https://doi.org/10.1097/pap.0000000000000161

• Update on tumor-infiltrating lymphocytes (TILs) in breast cancer, including recommendations to assess TILs in residual disease after neoadjuvant therapy and in carcinoma in situ: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer

  Seminars in Cancer Biology · 2017 · 10.1016/j.semcancer.2017.10.003

• Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method From the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in Invasive Breast Carcinoma and Ductal Carcinoma In Situ, Metastatic Tumor Deposits and Areas for Further Research

  Advances in Anatomic Pathology · 2017 · 10.1097/pap.0000000000000162

• Standardized evaluation of tumor-infiltrating lymphocytes in breast cancer: results of the ring studies of the international immuno-oncology biomarker working group

  Modern Pathology · 2016 · 10.1038/modpathol.2016.109

• Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy

  Nature Communications · 2016 · 10.1038/ncomms10582

• Genomic Characterization of Primary Invasive Lobular Breast Cancer

  Journal of Clinical Oncology · 2016 · 10.1200/jco.2015.64.0334

• Tumour-infiltrating lymphocytes in advanced HER2-positive breast cancer treated with pertuzumab or placebo in addition to trastuzumab and docetaxel: a retrospective analysis of the CLEOPATRA study

  The Lancet Oncology · 2016 · 10.1016/s1470-2045(16)30631-3

• Clinical relevance of host immunity in breast cancer: from TILs to the clinic

  Nature Reviews Clinical Oncology · 2015 · 10.1038/nrclinonc.2015.215

• RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors

  Clinical Cancer Research · 2015 · 10.1158/1078-0432.ccr-15-1125

• Tumor-Infiltrating Lymphocytes and Associations With Pathological Complete Response and Event-Free Survival in HER2-Positive Early-Stage Breast Cancer Treated With Lapatinib and Trastuzumab

  JAMA Oncology · 2015 · 10.1001/jamaoncol.2015.0830

• The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014

  Annals of Oncology · 2014 · 10.1093/annonc/mdu450

• Tumor infiltrating lymphocytes are prognostic in triple negative breast cancer and predictive for trastuzumab benefit in early breast cancer: results from the FinHER trial

  Annals of Oncology · 2014 · 10.1093/annonc/mdu112

• Prognostic and Predictive Value of Tumor-Infiltrating Lymphocytes in a Phase III Randomized Adjuvant Breast Cancer Trial in Node-Positive Breast Cancer Comparing the Addition of Docetaxel to Doxorubicin With Doxorubicin-Based Chemotherapy: BIG 02-98

  Journal of Clinical Oncology · 2013 · 10.1200/jco.2011.41.0902

• Liver metastases from colorectal adenocarcinomas grow in three patterns with different angiogenesis and desmoplasia

  The Journal of Pathology · 2001 · 10.1002/path.966

Current projects

No projects listed.