Carmen J. Allegra

Research interests

Publications

• ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal–Anal Task Forces whitepaper

  Nature Reviews Clinical Oncology · 2020 · https://doi.org/10.1038/s41571-020-0392-0

• Randomized Trial of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF-Mutant Metastatic Colorectal Cancer (SWOG S1406)

  Journal of Clinical Oncology · 2020 · https://doi.org/10.1200/jco.20.01994

• Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and the American Society of Clinical Oncology

  Journal of Clinical Oncology · 2017 · https://doi.org/10.1200/jco.2016.71.9807

• Extended RAS Gene Mutation Testing in Metastatic Colorectal Carcinoma to Predict Response to Anti–Epidermal Growth Factor Receptor Monoclonal Antibody Therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015

  Journal of Clinical Oncology · 2015 · https://doi.org/10.1200/jco.2015.63.9674

• Neoadjuvant 5-FU or Capecitabine Plus Radiation With or Without Oxaliplatin in Rectal Cancer Patients: A Phase III Randomized Clinical Trial

  JNCI Journal of the National Cancer Institute · 2015 · https://doi.org/10.1093/jnci/djv248

• Capecitabine and Oxaliplatin in the Preoperative Multimodality Treatment of Rectal Cancer: Surgical End Points From National Surgical Adjuvant Breast and Bowel Project Trial R-04

  Journal of Clinical Oncology · 2014 · https://doi.org/10.1200/jco.2013.53.7753

• Addition of Aflibercept to Fluorouracil, Leucovorin, and Irinotecan Improves Survival in a Phase III Randomized Trial in Patients With Metastatic Colorectal Cancer Previously Treated With an Oxaliplatin-Based Regimen

  Journal of Clinical Oncology · 2012 · https://doi.org/10.1200/jco.2012.42.8201

• Oxaliplatin As Adjuvant Therapy for Colon Cancer: Updated Results of NSABP C-07 Trial, Including Survival and Subset Analyses

  Journal of Clinical Oncology · 2011 · https://doi.org/10.1200/jco.2011.36.4539

• DNA Mismatch Repair Status and Colon Cancer Recurrence and Survival in Clinical Trials of 5-Fluorouracil-Based Adjuvant Therapy

  JNCI Journal of the National Cancer Institute · 2011 · https://doi.org/10.1093/jnci/djr153

• Phase III Trial Assessing Bevacizumab in Stages II and III Carcinoma of the Colon: Results of NSABP Protocol C-08

  Journal of Clinical Oncology · 2010 · https://doi.org/10.1200/jco.2010.30.0855

• National Institutes of Health State-of-the-Science Conference Statement: Diagnosis and Management of Ductal Carcinoma In Situ September 22-24, 2009

  JNCI Journal of the National Cancer Institute · 2010 · https://doi.org/10.1093/jnci/djp485

• Initial Safety Report of NSABP C-08: A Randomized Phase III Study of Modified FOLFOX6 With or Without Bevacizumab for the Adjuvant Treatment of Patients With Stage II or III Colon Cancer

  Journal of Clinical Oncology · 2009 · https://doi.org/10.1200/jco.2009.21.9220

• American Society of Clinical Oncology Provisional Clinical Opinion: Testing for KRAS Gene Mutations in Patients With Metastatic Colorectal Carcinoma to Predict Response to Anti–Epidermal Growth Factor Receptor Monoclonal Antibody Therapy

  Journal of Clinical Oncology · 2009 · https://doi.org/10.1200/jco.2009.21.9170

• Preoperative Multimodality Therapy Improves Disease-Free Survival in Patients With Carcinoma of the Rectum: NSABP R-03

  Journal of Clinical Oncology · 2009 · https://doi.org/10.1200/jco.2009.22.0467

• Prognostic and Predictive Roles of High-Degree Microsatellite Instability in Colon Cancer: A National Cancer Institute–National Surgical Adjuvant Breast and Bowel Project Collaborative Study

  Journal of Clinical Oncology · 2007 · https://doi.org/10.1200/jco.2006.05.8172

• Clinical Trial Designs for Predictive Marker Validation in Cancer Treatment Trials

  Journal of Clinical Oncology · 2005 · https://doi.org/10.1200/jco.2005.01.112

• Prognostic Value of Thymidylate Synthase, Ki-67, and p53 in Patients With Dukes’ B and C Colon Cancer: A National Cancer Institute–National Surgical Adjuvant Breast and Bowel Project Collaborative Study

  Journal of Clinical Oncology · 2003 · https://doi.org/10.1200/jco.2003.05.044

• The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer.

  Journal of Clinical Oncology · 1994 · https://doi.org/10.1200/jco.1994.12.12.2640

• Autoregulation of human thymidylate synthase messenger RNA translation by thymidylate synthase.

  Proceedings of the National Academy of Sciences · 1991 · https://doi.org/10.1073/pnas.88.20.8977

• Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates.

  Proceedings of the National Academy of Sciences · 1985 · https://doi.org/10.1073/pnas.82.15.4881

• Enhanced inhibition of thymidylate synthase by methotrexate polyglutamates.

  Journal of Biological Chemistry · 1985 · https://doi.org/10.1016/s0021-9258(17)39298-0

• Polyglutamation of methotrexate. Is methotrexate a prodrug?

  Journal of Clinical Investigation · 1985 · https://doi.org/10.1172/jci112088

Current projects

No projects listed.