Robert J. Wilkinson

Research interests

Publications

• T cell responses to SARS-CoV-2 spike cross-recognize Omicron

  Nature · 2022 · 10.1038/s41586-022-04460-3

• Final Analysis of a Trial of M72/AS01 E Vaccine to Prevent Tuberculosis

  New England Journal of Medicine · 2019 · 10.1056/nejmoa1909953

• Phase 2b Controlled Trial of M72/AS01 E Vaccine to Prevent Tuberculosis

  New England Journal of Medicine · 2018 · 10.1056/nejmoa1803484

• Tuberculous meningitis

  Nature Reviews Neurology · 2017 · 10.1038/nrneurol.2017.120

• Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages

  Nature Genetics · 2016 · 10.1038/ng.3704

• Management of latent Mycobacterium tuberculosis infection: WHO guidelines for low tuberculosis burden countries

  European Respiratory Journal · 2015 · https://doi.org/10.1183/13993003.01245-2015

• Diagnosis of Childhood Tuberculosis and Host RNA Expression in Africa

  New England Journal of Medicine · 2014 · 10.1056/nejmoa1303657

• The ongoing challenge of latent tuberculosis

  Philosophical Transactions of the Royal Society B Biological Sciences · 2014 · 10.1098/rstb.2013.0437

• Transcriptional Blood Signatures Distinguish Pulmonary Tuberculosis, Pulmonary Sarcoidosis, Pneumonias and Lung Cancers

  PLoS ONE · 2013 · 10.1371/journal.pone.0070630

• The Immune Response in Tuberculosis

  Annual Review of Immunology · 2013 · https://doi.org/10.1146/annurev-immunol-032712-095939

• Detection of Tuberculosis in HIV-Infected and -Uninfected African Adults Using Whole Blood RNA Expression Signatures: A Case-Control Study

  PLoS Medicine · 2013 · 10.1371/journal.pmed.1001538

• Predictive value of interferon-γ release assays for incident active tuberculosis: a systematic review and meta-analysis

  The Lancet Infectious Diseases · 2011 · https://doi.org/10.1016/s1473-3099(11)70210-9

• High-dose vitamin D3 during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial

  The Lancet · 2011 · 10.1016/s0140-6736(10)61889-2

• Tuberculous meningitis: a uniform case definition for use in clinical research

  The Lancet Infectious Diseases · 2010 · https://doi.org/10.1016/s1473-3099(10)70138-9

• Randomized placebo-controlled trial of prednisone for paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome

  AIDS · 2010 · 10.1097/qad.0b013e32833dfc68

• An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

  Nature · 2010 · https://doi.org/10.1038/nature09247

• The spectrum of latent tuberculosis: rethinking the biology and intervention strategies

  Nature Reviews Microbiology · 2009 · 10.1038/nrmicro2236

• Distinct, Specific IL-17- and IL-22-Producing CD4+ T Cell Subsets Contribute to the Human Anti-Mycobacterial Immune Response

  The Journal of Immunology · 2008 · 10.4049/jimmunol.180.3.1962

• Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings

  The Lancet Infectious Diseases · 2008 · 10.1016/s1473-3099(08)70184-1

• Neutrophil-mediated innate immune resistance to mycobacteria

  Journal of Clinical Investigation · 2007 · 10.1172/jci31097

• A Single Dose of Vitamin D Enhances Immunity to Mycobacteria

  American Journal of Respiratory and Critical Care Medicine · 2007 · 10.1164/rccm.200701-007oc

• IFN-γ- and TNF-Independent Vitamin D-Inducible Human Suppression of Mycobacteria: The Role of Cathelicidin LL-37

  The Journal of Immunology · 2007 · 10.4049/jimmunol.178.11.7190

• Rapid Detection of Mycobacterium tuberculosis Infection by Enumeration of Antigen-specific T Cells

  American Journal of Respiratory and Critical Care Medicine · 2001 · 10.1164/ajrccm.163.4.2009100

• Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: a case-control study

  The Lancet · 2000 · 10.1016/s0140-6736(99)02301-6

• Human cytolytic and interferon γ-secreting CD8 + T lymphocytes specific for Mycobacterium tuberculosis

  Proceedings of the National Academy of Sciences · 1998 · 10.1073/pnas.95.1.270

Current projects

No projects listed.