Fredrik Bäckhed

Research interests

Publications

• Developmental trajectory of the healthy human gut microbiota during the first 5 years of life

  Cell Host & Microbe · 2021 · https://doi.org/10.1016/j.chom.2021.02.021

• Gut microbial metabolites as multi-kingdom intermediates

  Nature Reviews Microbiology · 2020 · 10.1038/s41579-020-0438-4

• Depicting the composition of gut microbiota in a population with varied ethnic origins but shared geography

  Nature Medicine · 2018 · https://doi.org/10.1038/s41591-018-0160-1

• Aberrant intestinal microbiota in individuals with prediabetes

  Diabetologia · 2018 · https://doi.org/10.1007/s00125-018-4550-1

• An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans

  Cell Metabolism · 2018 · https://doi.org/10.1016/j.cmet.2018.01.005

• Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks

  Proceedings of the National Academy of Sciences · 2018 · https://doi.org/10.1073/pnas.1720017115

• The Impact of Dietary Fiber on Gut Microbiota in Host Health and Disease

  Cell Host & Microbe · 2018 · 10.1016/j.chom.2018.05.012

• Enterotypes in the landscape of gut microbial community composition

  Nature Microbiology · 2017 · 10.1038/s41564-017-0072-8

• Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

  Nature Medicine · 2017 · 10.1038/nm.4345

• Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism

  Cell Metabolism · 2016 · 10.1016/j.cmet.2016.05.005

• Signals from the gut microbiota to distant organs in physiology and disease

  Nature Medicine · 2016 · 10.1038/nm.4185

• From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

  Cell · 2016 · https://doi.org/10.1016/j.cell.2016.05.041

• Diet–microbiota interactions as moderators of human metabolism

  Nature · 2016 · 10.1038/nature18846

• Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life

  Cell Host & Microbe · 2015 · 10.1016/j.chom.2015.04.004

• Dietary Fiber-Induced Improvement in Glucose Metabolism Is Associated with Increased Abundance of Prevotella

  Cell Metabolism · 2015 · 10.1016/j.cmet.2015.10.001

• Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation

  Cell Metabolism · 2015 · 10.1016/j.cmet.2015.07.009

• Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits

  Cell · 2014 · 10.1016/j.cell.2013.12.016

• Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

  Cell Metabolism · 2013 · 10.1016/j.cmet.2013.01.003

• Gut metagenome in European women with normal, impaired and diabetic glucose control

  Nature · 2013 · 10.1038/nature12198

• The gut microbiota — masters of host development and physiology

  Nature Reviews Microbiology · 2013 · 10.1038/nrmicro2974

• Functional interactions between the gut microbiota and host metabolism

  Nature · 2012 · https://doi.org/10.1038/nature11552

• Symptomatic atherosclerosis is associated with an altered gut metagenome

  Nature Communications · 2012 · 10.1038/ncomms2266

• Host Remodeling of the Gut Microbiome and Metabolic Changes during Pregnancy

  Cell · 2012 · 10.1016/j.cell.2012.07.008

• Human oral, gut, and plaque microbiota in patients with atherosclerosis

  Proceedings of the National Academy of Sciences · 2010 · 10.1073/pnas.1011383107

• Comparative Analysis of Human Gut Microbiota by Barcoded Pyrosequencing

  PLoS ONE · 2008 · 10.1371/journal.pone.0002836

• Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

  Cell Host & Microbe · 2008 · 10.1016/j.chom.2008.02.015

• Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

  Proceedings of the National Academy of Sciences · 2008 · 10.1073/pnas.0808567105

• Mechanisms underlying the resistance to diet-induced obesity in germ-free mice

  Proceedings of the National Academy of Sciences · 2007 · 10.1073/pnas.0605374104

• Host-Bacterial Mutualism in the Human Intestine

  Science · 2005 · https://doi.org/10.1126/science.1104816

• Obesity alters gut microbial ecology

  Proceedings of the National Academy of Sciences · 2005 · https://doi.org/10.1073/pnas.0504978102

• The gut microbiota as an environmental factor that regulates fat storage

  Proceedings of the National Academy of Sciences · 2004 · https://doi.org/10.1073/pnas.0407076101

Current projects

No projects listed.