Yang Liao

Research interests

Publications

• MYB orchestrates T cell exhaustion and response to checkpoint inhibition

  Nature · 2022 · 10.1038/s41586-022-05105-1

• Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma

  Nature Immunology · 2021 · 10.1038/s41590-021-00943-z

• Sex-specific adipose tissue imprinting of regulatory T cells

  Nature · 2020 · 10.1038/s41586-020-2040-3

• Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis

  Nature Communications · 2020 · 10.1038/s41467-019-14112-2

• IRF4 Activity Is Required in Established Plasma Cells to Regulate Gene Transcription and Mitochondrial Homeostasis

  Cell Reports · 2019 · 10.1016/j.celrep.2019.10.097

• The R package Rsubread is easier, faster, cheaper and better for alignment and quantification of RNA sequencing reads

  Nucleic Acids Research · 2019 · https://doi.org/10.1093/nar/gkz114

• c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host–microbiota homeostasis

  Nature Immunology · 2019 · 10.1038/s41590-019-0316-2

• IMiDs prime myeloma cells for daratumumab-mediated cytotoxicity through loss of Ikaros and Aiolos

  Blood · 2018 · 10.1182/blood-2018-05-850727

• Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB

  Nature Communications · 2017 · 10.1038/s41467-017-01605-1

• The TNF Receptor Superfamily-NF-κB Axis Is Critical to Maintain Effector Regulatory T Cells in Lymphoid and Non-lymphoid Tissues

  Cell Reports · 2017 · 10.1016/j.celrep.2017.08.068

• Transcription Factor IRF4 Promotes CD8+ T Cell Exhaustion and Limits the Development of Memory-like T Cells during Chronic Infection

  Immunity · 2017 · https://doi.org/10.1016/j.immuni.2017.11.021

• Effector Regulatory T Cell Differentiation and Immune Homeostasis Depend on the Transcription Factor Myb

  Immunity · 2017 · 10.1016/j.immuni.2016.12.017

• A molecular threshold for effector CD8+ T cell differentiation controlled by transcription factors Blimp-1 and T-bet

  Nature Immunology · 2016 · 10.1038/ni.3410

• Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response

  Nature Immunology · 2016 · 10.1038/ni.3348

• Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

  Science · 2016 · https://doi.org/10.1126/science.aad2035

• Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells

  Nature Immunology · 2015 · 10.1038/ni.3154

• The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells

  Nature Immunology · 2015 · https://doi.org/10.1038/ni.3085

• Assessing technical performance in differential gene expression experiments with external spike-in RNA control ratio mixtures

  Nature Communications · 2014 · 10.1038/ncomms6125

• Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia

  Genes & Development · 2014 · 10.1101/gad.240416.114

• A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium

  Nature Biotechnology · 2014 · https://doi.org/10.1038/nbt.2957

• featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

  Bioinformatics · 2013 · 10.1093/bioinformatics/btt656

• The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote

  Nucleic Acids Research · 2013 · 10.1093/nar/gkt214

Current projects

No projects listed.