Thomas Gasser

Research interests

Publications

• Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease

  npj Parkinson s Disease · 2021 · https://doi.org/10.1038/s41531-021-00203-9

• Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets

  JAMA Neurology · 2021 · https://doi.org/10.1001/jamaneurol.2020.5257

• Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome

  Nature Communications · 2021 · https://doi.org/10.1038/s41467-021-26280-1

• Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture

  Nature Genetics · 2021 · https://doi.org/10.1038/s41588-021-00785-3

• LifeTime and improving European healthcare through cell-based interceptive medicine

  Nature · 2020 · https://doi.org/10.1038/s41586-020-2715-9

• Parkinson’s disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions

  BMC Biology · 2020 · https://doi.org/10.1186/s12915-020-00775-7

• A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

  Acta Neuropathologica · 2019 · https://doi.org/10.1007/s00401-019-02026-8

• Update of the MDS research criteria for prodromal Parkinson's disease

  Movement Disorders · 2019 · 10.1002/mds.27802

• Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

  The Lancet Neurology · 2019 · https://doi.org/10.1016/s1474-4422(19)30320-5

• NeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases

  Neurobiology of Aging · 2017 · https://doi.org/10.1016/j.neurobiolaging.2017.05.009

• MDS research criteria for prodromal Parkinson's disease

  Movement Disorders · 2015 · https://doi.org/10.1002/mds.26431

• MDS clinical diagnostic criteria for Parkinson's disease

  Movement Disorders · 2015 · https://doi.org/10.1002/mds.26424

• Time to redefine PD? Introductory statement of the MDS Task Force on the definition of Parkinson's disease

  Movement Disorders · 2014 · https://doi.org/10.1002/mds.25844

• Parkinson’s disease in GTP cyclohydrolase 1 mutation carriers

  Brain · 2014 · https://doi.org/10.1093/brain/awu179

• Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

  Nature Genetics · 2014 · https://doi.org/10.1038/ng.3043

• The natural history of multiple system atrophy: a prospective European cohort study

  The Lancet Neurology · 2013 · https://doi.org/10.1016/s1474-4422(12)70327-7

• A Multicenter Study of Glucocerebrosidase Mutations in Dementia With Lewy Bodies

  JAMA Neurology · 2013 · https://doi.org/10.1001/jamaneurol.2013.1925

• Large-scale replication and heterogeneity in Parkinson disease genetic loci

  Neurology · 2012 · https://doi.org/10.1212/wnl.0b013e318264e353

• Postoperative radiotherapy after radical prostatectomy for high-risk prostate cancer: long-term results of a randomised controlled trial (EORTC trial 22911)

  The Lancet · 2012 · https://doi.org/10.1016/s0140-6736(12)61253-7

• Large-scale replication and heterogeneity in Parkinson disease genetic loci

  Neurology · 2012 · https://doi.org/10.1212/wnl.0b013e318264e353

• Presentation, diagnosis, and management of multiple system atrophy in Europe: Final analysis of the European multiple system atrophy registry

  Movement Disorders · 2010 · https://doi.org/10.1002/mds.23192

• SNCA variants are associated with increased risk for multiple system atrophy

  Annals of Neurology · 2009 · https://doi.org/10.1002/ana.21685

• Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

  New England Journal of Medicine · 2009 · https://doi.org/10.1056/nejmoa0901281

• Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria

  The Lancet Neurology · 2009 · 10.1016/s1474-4422(09)70238-8

• Genome-wide association study reveals genetic risk underlying Parkinson's disease

  Nature Genetics · 2009 · 10.1038/ng.487

• Red flags for multiple system atrophy

  Movement Disorders · 2008 · https://doi.org/10.1002/mds.21992

• Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study

  The Lancet Neurology · 2008 · 10.1016/s1474-4422(08)70117-0

• Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology

  Neuron · 2004 · https://doi.org/10.1016/j.neuron.2004.11.005

• Cross-modal plasticity for sensory and motor activation patterns in blind subjects

  NeuroImage · 2003 · https://doi.org/10.1016/s1053-8119(03)00114-9

• The phenotypic spectrum of CADASIL: Clinical findings in 102 cases

  Annals of Neurology · 1998 · 10.1002/ana.410440506

Current projects

No projects listed.