Jens Wiltfang

Research interests

Publications

• Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer’s disease (DELCODE)

  Alzheimer s Research & Therapy · 2018 · 10.1186/s13195-017-0314-2

• Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry

  The World Journal of Biological Psychiatry · 2017 · 10.1080/15622975.2017.1375556

• Prevalence and prognosis of Alzheimer’s disease at the mild cognitive impairment stage

  Brain · 2015 · 10.1093/brain/awv029

• Deep brain stimulation of the nucleus basalis of Meynert in Alzheimer’s dementia

  Molecular Psychiatry · 2014 · 10.1038/mp.2014.32

• The mechanism of γ‐Secretase dysfunction in familial Alzheimer disease

  The EMBO Journal · 2012 · 10.1038/emboj.2012.79

• Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

  Nature Genetics · 2011 · https://doi.org/10.1038/ng.803

• Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease

  PLoS ONE · 2010 · https://doi.org/10.1371/journal.pone.0013950

• Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

  Nature Genetics · 2009 · https://doi.org/10.1038/ng.440

• Social cognition in attention-deficit hyperactivity disorder (ADHD)

  Neuroscience & Biobehavioral Reviews · 2009 · 10.1016/j.neubiorev.2009.10.009

• γ-Secretase Heterogeneity in the Aph1 Subunit: Relevance for Alzheimer’s Disease

  Science · 2009 · 10.1126/science.1171176

• Therapeutic approaches to Alzheimer's disease

  Brain · 2006 · 10.1093/brain/awl280

• Amyloid β peptide ratio 42/40 but not Aβ42 correlates with phospho‐Tau in patients with low‐ and high‐CSF Aβ40 load

  Journal of Neurochemistry · 2006 · 10.1111/j.1471-4159.2006.04404.x

• Presenilin clinical mutations can affect γ‐secretase activity by different mechanisms

  Journal of Neurochemistry · 2006 · 10.1111/j.1471-4159.2005.03578.x

• Growth and transplantation of a custom vascularised bone graft in a man

  The Lancet · 2004 · https://doi.org/10.1016/s0140-6736(04)16935-3

• Morbidity of harvesting of bone grafts from the iliac crest for preprosthetic augmentation procedures: A prospective study

  International Journal of Oral and Maxillofacial Surgery · 2004 · 10.1054/ijom.2003.0465

• Phospho-tau/total tau ratio in cerebrospinal fluid discriminates Creutzfeldt–Jakob disease from other dementias

  Molecular Psychiatry · 2003 · 10.1038/sj.mp.4001220

• Neurochemical diagnosis of Alzheimer’s dementia by CSF Aβ42, Aβ42/Aβ40 ratio and total tau

  Neurobiology of Aging · 2003 · 10.1016/s0197-4580(03)00086-1

• Value of CSF β-amyloid1–42 and tau as predictors of Alzheimer's disease in patients with mild cognitive impairment

  Molecular Psychiatry · 2003 · 10.1038/sj.mp.4001473

• Tau protein and 14-3-3 protein in the differential diagnosis of Creutzfeldt–Jakob disease

  Neurology · 2002 · 10.1212/wnl.58.2.192

• Highly conserved and disease‐specific patterns of carboxyterminally truncated Aβ peptides 1–37/38/39 in addition to 1–40/42 in Alzheimer's disease and in patients with chronic neuroinflammation

  Journal of Neurochemistry · 2002 · 10.1046/j.1471-4159.2002.00818.x

• Degradation characteristics of α and β tri‐calcium‐phosphate (TCP) in minipigs

  Journal of Biomedical Materials Research · 2002 · 10.1002/jbm.10084

• Large‐scale, multicenter study of cerebrospinal fluid tau protein phosphorylated at serine 199 for the antemortem diagnosis of Alzheimer's disease

  Annals of Neurology · 2001 · 10.1002/ana.1054

• Improved discrimination of AD patients using β-amyloid (1-42) and tau levels in CSF

  Neurology · 1999 · https://doi.org/10.1212/wnl.52.8.1555

• Detection of 14‐3‐3 protein in the cerebrospinal fluid supports the diagnosis of Creutzfeldt‐Jakob disease

  Annals of Neurology · 1998 · 10.1002/ana.410430109

• Elevated levels of tau-protein in cerebrospinal fluid of patients with Creutzfeldt–Jakob disease

  Neuroscience Letters · 1997 · 10.1016/s0304-3940(97)00215-2

Current projects

No projects listed.