Paul J. Thornalley
Researcher Next ID · RN-028422
Researcher · Biochemistry, Genetics and Molecular Biology
Coventry, Qatar
- Works count
- 444
- Citation count
- 37,269
- H-index
- 100
- i10-index
- 285
Research interests
Publications
Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo
Nature Metabolism · 2022 · https://doi.org/10.1038/s42255-022-00591-z
Improved Glycemic Control and Vascular Function in Overweight and Obese Subjects by Glyoxalase 1 Inducer Formulation
Diabetes · 2016 · https://doi.org/10.2337/db16-0153
Methylglyoxal-induced dicarbonyl stress in aging and disease: first steps towards glyoxalase 1-based treatments
Clinical Science · 2016 · https://doi.org/10.1042/cs20160025
Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics
Glycoconjugate Journal · 2016 · https://doi.org/10.1007/s10719-016-9705-z
Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy
Nature Medicine · 2012 · https://doi.org/10.1038/nm.2750
Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation
Biochemical Journal · 2011 · https://doi.org/10.1042/bj20111648
Unraveling the Biological Roles of Reactive Oxygen Species
Cell Metabolism · 2011 · https://doi.org/10.1016/j.cmet.2011.03.010
Glyoxalase in ageing
Seminars in Cell and Developmental Biology · 2011 · https://doi.org/10.1016/j.semcdb.2011.02.013
Glycation of LDL by Methylglyoxal Increases Arterial Atherogenicity
Diabetes · 2011 · https://doi.org/10.2337/db11-0085
Activation of NF-E2–Related Factor-2 Reverses Biochemical Dysfunction of Endothelial Cells Induced by Hyperglycemia Linked to Vascular Disease
Diabetes · 2008 · https://doi.org/10.2337/db06-1003
Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose
Biochemical Journal · 1999 · https://doi.org/10.1042/bj3440109
The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life
Biochemical Journal · 1990 · https://doi.org/10.1042/bj2690001
Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · 1985 · https://doi.org/10.1016/0167-4838(85)90098-6
Current projects
No projects listed.