Naila Rabbani

Research interests

Publications

• Hexokinase-2 Glycolytic Overload in Diabetes and Ischemia–Reperfusion Injury

  Trends in Endocrinology and Metabolism · 2019 · 10.1016/j.tem.2019.04.011

• Advanced glycation end products in the pathogenesis of chronic kidney disease

  Kidney International · 2018 · 10.1016/j.kint.2017.11.034

• Involvement of a gut–retina axis in protection against dietary glycemia-induced age-related macular degeneration

  Proceedings of the National Academy of Sciences · 2017 · 10.1073/pnas.1702302114

• Improved Glycemic Control and Vascular Function in Overweight and Obese Subjects by Glyoxalase 1 Inducer Formulation

  Diabetes · 2016 · https://doi.org/10.2337/db16-0153

• Methylglyoxal-induced dicarbonyl stress in aging and disease: first steps towards glyoxalase 1-based treatments

  Clinical Science · 2016 · https://doi.org/10.1042/cs20160025

• Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics

  Glycoconjugate Journal · 2016 · https://doi.org/10.1007/s10719-016-9705-z

• Dicarbonyl stress in cell and tissue dysfunction contributing to ageing and disease

  Biochemical and Biophysical Research Communications · 2015 · 10.1016/j.bbrc.2015.01.140

• Dicarbonyl proteome and genome damage in metabolic and vascular disease

  Biochemical Society Transactions · 2014 · 10.1042/bst20140018

• Measurement of methylglyoxal by stable isotopic dilution analysis LC-MS/MS with corroborative prediction in physiological samples

  Nature Protocols · 2014 · 10.1038/nprot.2014.129

• The Critical Role of Methylglyoxal and Glyoxalase 1 in Diabetic Nephropathy

  Diabetes · 2013 · 10.2337/db13-1606

• Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

  Nature Medicine · 2012 · https://doi.org/10.1038/nm.2750

• Glyoxalase in diabetes, obesity and related disorders

  Seminars in Cell and Developmental Biology · 2011 · 10.1016/j.semcdb.2011.02.015

• Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation

  Biochemical Journal · 2011 · 10.1042/bj20111648

• Glyoxalase in ageing

  Seminars in Cell and Developmental Biology · 2011 · https://doi.org/10.1016/j.semcdb.2011.02.013

• Glycation of LDL by Methylglyoxal Increases Arterial Atherogenicity

  Diabetes · 2011 · https://doi.org/10.2337/db11-0085

• Glyoxalase in tumourigenesis and multidrug resistance

  Seminars in Cell and Developmental Biology · 2011 · 10.1016/j.semcdb.2011.02.006

• Glycation research in amino acids: a place to call home

  Amino Acids · 2010 · 10.1007/s00726-010-0782-1

• Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome

  Amino Acids · 2010 · 10.1007/s00726-010-0783-0

• C. elegans as Model for the Study of High Glucose– Mediated Life Span Reduction

  Diabetes · 2009 · 10.2337/db09-0567

• Advanced Glycation End Products in Extracellular Matrix Proteins Contribute to the Failure of Sensory Nerve Regeneration in Diabetes

  Diabetes · 2009 · 10.2337/db09-0320

• Activation of NF-E2–Related Factor-2 Reverses Biochemical Dysfunction of Endothelial Cells Induced by Hyperglycemia Linked to Vascular Disease

  Diabetes · 2008 · https://doi.org/10.2337/db06-1003

• Dicarbonyls linked to damage in the powerhouse: glycation of mitochondrial proteins and oxidative stress

  Biochemical Society Transactions · 2008 · 10.1042/bst0361045

• High-dose thiamine therapy for patients with type 2 diabetes and microalbuminuria: a randomised, double-blind placebo-controlled pilot study

  Diabetologia · 2008 · 10.1007/s00125-008-1224-4

• High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease

  Diabetologia · 2007 · 10.1007/s00125-007-0771-4

• High Glucose Increases Angiopoietin-2 Transcription in Microvascular Endothelial Cells through Methylglyoxal Modification of mSin3A

  Journal of Biological Chemistry · 2007 · 10.1074/jbc.m704703200

Current projects

No projects listed.