Christopher D. Buckley

Research interests

Publications

• Fibroblasts as immune regulators in infection, inflammation and cancer

  Nature reviews. Immunology · 2021 · https://doi.org/10.1038/s41577-021-00540-z

• Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis

  Nature Medicine · 2020 · https://doi.org/10.1038/s41591-020-0939-8

• Notch signalling drives synovial fibroblast identity and arthritis pathology

  Nature · 2020 · https://doi.org/10.1038/s41586-020-2222-z

• Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes

  Cell Reports · 2019 · https://doi.org/10.1016/j.celrep.2019.07.091

• Distinct fibroblast subsets drive inflammation and damage in arthritis

  Nature · 2019 · https://doi.org/10.1038/s41586-019-1263-7

• Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-02892-y

• Induction and transcriptional regulation of the co-inhibitory gene module in T cells

  Nature · 2018 · https://doi.org/10.1038/s41586-018-0206-z

• Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis

  Nature · 2017 · https://doi.org/10.1038/nature20810

• EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update

  Annals of the Rheumatic Diseases · 2017 · https://doi.org/10.1136/annrheumdis-2016-210715

• Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets

  Journal of Clinical Investigation · 2015 · https://doi.org/10.1172/jci79070

• Cytokines in rheumatoid arthritis — shaping the immunological landscape

  Nature Reviews Rheumatology · 2015 · https://doi.org/10.1038/nrrheum.2015.171

• Proresolving Lipid Mediators and Mechanisms in the Resolution of Acute Inflammation

  Immunity · 2014 · https://doi.org/10.1016/j.immuni.2014.02.009

• The resolution of inflammation

  Nature reviews. Immunology · 2012 · https://doi.org/10.1038/nri3362

• IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4−CD8− entheseal resident T cells

  Nature Medicine · 2012 · https://doi.org/10.1038/nm.2817

• EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis

  Annals of the Rheumatic Diseases · 2012 · https://doi.org/10.1136/annrheumdis-2011-200990

• Altered expression of microRNA‐203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation

  Arthritis & Rheumatism · 2010 · https://doi.org/10.1002/art.30115

• The porin OmpD from nontyphoidal Salmonella is a key target for a protective B1b cell antibody response

  Proceedings of the National Academy of Sciences · 2009 · https://doi.org/10.1073/pnas.0812431106

• Periodontitis in systemic rheumatic diseases

  Nature Reviews Rheumatology · 2009 · https://doi.org/10.1038/nrrheum.2009.28

• Resolution of in flammation: state of the art, definitions and terms

  The FASEB Journal · 2007 · 10.1096/fj.06-7227rev

• Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin

  Arthritis Research & Therapy · 2005 · https://doi.org/10.1186/ar1733

• Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment

  Nature · 2002 · https://doi.org/10.1038/nature00811

• Ectopic expression of the B cell-attracting chemokine BCA-1 (CXCL13) on endothelial cells and within lymphoid follicles contributes to the establishment of germinal center-like structures in Sj�gren's syndrome

  Arthritis & Rheumatism · 2001 · https://doi.org/10.1002/1529-0131(200111)44:11<2633::aid-art443>3.0.co;2-9

• Fibroblasts regulate the switch from acute resolving to chronic persistent inflammation

  Trends in Immunology · 2001 · https://doi.org/10.1016/s1471-4906(01)01863-4

• The Small Gtpase, Rap1, Mediates Cd31-Induced Integrin Adhesion

  The Journal of Cell Biology · 2000 · https://doi.org/10.1083/jcb.148.6.1151

• RGD peptides induce apoptosis by direct caspase-3 activation

  Nature · 1999 · https://doi.org/10.1038/17409

Current projects

No projects listed.