Timothy D. W. Claridge

Research interests

Publications

• Global aromaticity at the nanoscale

  Nature Chemistry · 2020 · https://doi.org/10.1038/s41557-019-0398-3

• How formaldehyde reacts with amino acids

  Communications Chemistry · 2019 · https://doi.org/10.1038/s42004-019-0224-2

• Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials

  Chemical Science · 2017 · https://doi.org/10.1039/c7sc02103h

• Interaction of Avibactam with Class B Metallo-β-Lactamases

  Antimicrobial Agents and Chemotherapy · 2016 · 10.1128/aac.00897-16

• Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity

  Science · 2016 · https://doi.org/10.1126/science.aag1465

• Aromatic and antiaromatic ring currents in a molecular nanoring

  Nature · 2016 · https://doi.org/10.1038/nature20798

• Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases

  Nature Communications · 2016 · 10.1038/ncomms12673

• High-Resolution NMR Techniques in Organic Chemistry

  Elsevier eBooks · 2016 · https://doi.org/10.1016/c2015-0-04654-8

• Self-Assembly of Russian Doll Concentric Porphyrin Nanorings

  Journal of the American Chemical Society · 2015 · 10.1021/jacs.5b07956

• Caterpillar Track Complexes in Template‐Directed Synthesis and Correlated Molecular Motion

  Angewandte Chemie International Edition · 2015 · 10.1002/anie.201412293

• Rhodanine hydrolysis leads to potent thioenolate mediated metallo-β-lactamase inhibition

  Nature Chemistry · 2014 · 10.1038/nchem.2110

• Fluorescent Charge-Assisted Halogen-Bonding Macrocyclic Halo-Imidazolium Receptors for Anion Recognition and Sensing in Aqueous Media

  Journal of the American Chemical Society · 2012 · https://doi.org/10.1021/ja302213r

• Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans

  Nature Chemical Biology · 2012 · 10.1038/nchembio.1093

• The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases

  EMBO Reports · 2011 · https://doi.org/10.1038/embor.2011.43

• Vernier templating and synthesis of a 12-porphyrin nano-ring

  Nature · 2010 · https://doi.org/10.1038/nature09683

• From Disulfide‐ to Thioether‐Linked Glycoproteins

  Angewandte Chemie International Edition · 2008 · 10.1002/anie.200704381

• Homo- and Hetero-[3]Rotaxanes with Two π-Systems Clasped in a Single Macrocycle

  Journal of the American Chemical Society · 2006 · 10.1021/ja0665139

• Hypoxia-inducible factor prolyl hydroxylase 2 has a high affinity for ferrous iron and 2-oxoglutarate

  Molecular BioSystems · 2005 · 10.1039/b511249b

• Unidirectional Photoinduced Shuttling in a Rotaxane with a Symmetric Stilbene Dumbbell

  Angewandte Chemie International Edition · 2002 · https://doi.org/10.1002/1521-3773(20020517)41:10<1769::aid-anie1769>3.0.co;2-n

• Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the β-carbon of asparagine-803

  Biochemical Journal · 2002 · https://doi.org/10.1042/bj20021162

• Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL

  Nature · 2002 · https://doi.org/10.1038/nature00767

• Rotaxane-Encapsulation Enhances the Stability of an Azo Dye, in Solution and when Bonded to Cellulose

  Angewandte Chemie International Edition · 2001 · 10.1002/1521-3773(20010316)40:6<1071::aid-anie10710>3.0.co;2-5

• 10-Helical conformations in oxetane β-amino acid hexamers

  Tetrahedron Letters · 2001 · 10.1016/s0040-4039(01)00661-x

• Azo‐Dye Rotaxanes

  Angewandte Chemie International Edition in English · 1997 · 10.1002/anie.199713101

• Inhibition of Human Leukocyte and Porcine Pancreatic Elastase by Homologues of Bovine Pancreatic Trypsin Inhibitor

  Biochemistry · 1996 · https://doi.org/10.1021/bi953013b

Current projects

No projects listed.