David J. Brooks

Research interests

Publications

• Brain-first versus body-first Parkinson’s disease: a multimodal imaging case-control study

  Brain · 2020 · 10.1093/brain/awaa238

• Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

  Movement Disorders · 2017 · https://doi.org/10.1002/mds.27115

• The DESI Experiment Part I: Science,Targeting, and Survey Design

  arXiv (Cornell University) · 2016 · https://doi.org/10.48550/arxiv.1611.00036

• Neuroinflammation in Alzheimer's disease

  The Lancet Neurology · 2015 · https://doi.org/10.1016/s1474-4422(15)70016-5

• Prevalence of Amyloid PET Positivity in Dementia Syndromes

  JAMA · 2015 · https://doi.org/10.1001/jama.2015.4669

• Prevalence of Cerebral Amyloid Pathology in Persons Without Dementia

  JAMA · 2015 · https://doi.org/10.1001/jama.2015.4668

• The Parkinson Progression Marker Initiative (PPMI)

  Progress in Neurobiology · 2011 · https://doi.org/10.1016/j.pneurobio.2011.09.005

• Inflammation after trauma: Microglial activation and traumatic brain injury

  Annals of Neurology · 2011 · 10.1002/ana.22455

• 11C-PiB PET assessment of change in fibrillar amyloid-β load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study

  The Lancet Neurology · 2010 · 10.1016/s1474-4422(10)70043-0

• Conversion of amyloid positive and negative MCI to AD over 3 years

  Neurology · 2009 · 10.1212/wnl.0b013e3181b23564

• Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study

  Neurobiology of Disease · 2008 · 10.1016/j.nbd.2008.08.001

• Second consensus statement on the diagnosis of multiple system atrophy

  Neurology · 2008 · https://doi.org/10.1212/01.wnl.0000324625.00404.15

• Amyloid, hypometabolism, and cognition in Alzheimer disease

  Neurology · 2006 · 10.1212/01.wnl.0000244749.20056.d4

• Randomized controlled trial of intraputamenal glial cell line–derived neurotrophic factor infusion in Parkinson disease

  Annals of Neurology · 2006 · 10.1002/ana.20737

• In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease

  Neurobiology of Disease · 2005 · 10.1016/j.nbd.2005.08.002

• Depression in Parkinson's disease: loss of dopamine and noradrenaline innervation in the limbic system

  Brain · 2005 · 10.1093/brain/awh445

• Rasagiline as an adjunct to levodopa in patients with Parkinson's disease and motor fluctuations (LARGO, Lasting effect in Adjunct therapy with Rasagiline Given Once daily, study): a randomised, double-blind, parallel-group trial

  The Lancet · 2005 · 10.1016/s0140-6736(05)71083-7

• Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study

  Neurobiology of Disease · 2004 · 10.1016/j.nbd.2003.12.012

• Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL‐PET study

  Annals of Neurology · 2003 · 10.1002/ana.10609

• Direct brain infusion of glial cell line–derived neurotrophic factor in Parkinson disease

  Nature Medicine · 2003 · 10.1038/nm850

• Three‐dimensional maximum probability atlas of the human brain, with particular reference to the temporal lobe

  Human Brain Mapping · 2003 · 10.1002/hbm.10123

• In-vivo measurement of activated microglia in dementia

  The Lancet · 2001 · 10.1016/s0140-6736(01)05625-2

• A Five-Year Study of the Incidence of Dyskinesia in Patients with Early Parkinson's Disease Who Were Treated with Ropinirole or Levodopa

  New England Journal of Medicine · 2000 · https://doi.org/10.1056/nejm200005183422004

• Self-initiated versus externally triggered movements

  Brain · 2000 · 10.1093/brain/123.6.1216

• Evidence for striatal dopamine release during a video game

  Nature · 1998 · 10.1038/30498

• Self-initiated versus externally triggered movements

  Brain · 1995 · 10.1093/brain/118.4.913

• Motor sequence learning: a study with positron emission tomography

  Journal of Neuroscience · 1994 · 10.1523/jneurosci.14-06-03775.1994

• Survival of Implanted Fetal Dopamine Cells and Neurologic Improvement 12 to 46 Months after Transplantation for Parkinson's Disease

  New England Journal of Medicine · 1992 · 10.1056/nejm199211263272202

• Core assessment program for intracerebral transplantations (CAPIT)

  Movement Disorders · 1992 · 10.1002/mds.870070103

• The functional anatomy of motor recovery after stroke in humans: A study with positron emission tomography

  Annals of Neurology · 1991 · 10.1002/ana.410290112

Current projects

No projects listed.