Philip Goulder

Research interests

Publications

• Antibody escape of SARS-CoV-2 Omicron BA.4 and BA.5 from vaccine and BA.1 serum

  Cell · 2022 · https://doi.org/10.1016/j.cell.2022.06.005

• Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine

  Cell · 2021 · https://doi.org/10.1016/j.cell.2021.10.011

• Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum

  Cell · 2021 · https://doi.org/10.1016/j.cell.2021.06.020

• Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern

  Nature Communications · 2021 · https://doi.org/10.1038/s41467-021-25167-5

• Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19

  Nature Immunology · 2020 · https://doi.org/10.1038/s41590-020-0782-6

• CD39 Expression Identifies Terminally Exhausted CD8+ T Cells

  PLoS Pathogens · 2015 · https://doi.org/10.1371/journal.ppat.1005177

• Sex Differences in Pediatric Infectious Diseases

  The Journal of Infectious Diseases · 2014 · https://doi.org/10.1093/infdis/jiu232

• Influence of HLA-C Expression Level on HIV Control

  Science · 2013 · https://doi.org/10.1126/science.1232685

• HIV and HLA Class I: An Evolving Relationship

  Immunity · 2012 · 10.1016/j.immuni.2012.09.005

• Adaptation of HIV-1 to human leukocyte antigen class I

  Nature · 2009 · https://doi.org/10.1038/nature07746

• Impact of MHC class I diversity on immune control of immunodeficiency virus replication

  Nature reviews. Immunology · 2008 · https://doi.org/10.1038/nri2357

• PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

  Nature · 2006 · https://doi.org/10.1038/nature05115

• CD8+ T-cell responses to different HIV proteins have discordant associations with viral load

  Nature Medicine · 2006 · https://doi.org/10.1038/nm1520

• Fitness Cost of Escape Mutations in p24 Gag in Association with Control of Human Immunodeficiency Virus Type 1

  Journal of Virology · 2006 · https://doi.org/10.1128/jvi.80.7.3617-3623.2006

• Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA

  Nature · 2004 · https://doi.org/10.1038/nature03113

• HIV and SIV CTL escape: implications for vaccine design

  Nature reviews. Immunology · 2004 · https://doi.org/10.1038/nri1417

• HIV evolution: CTL escape mutation and reversion after transmission

  Nature Medicine · 2004 · https://doi.org/10.1038/nm992

• Comprehensive Epitope Analysis of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T-Cell Responses Directed against the Entire Expressed HIV-1 Genome Demonstrate Broadly Directed Responses, but No Correlation to Viral Load

  Journal of Virology · 2003 · https://doi.org/10.1128/jvi.77.3.2081-2092.2003

• Clustered Mutations in HIV-1 Gag Are Consistently Required for Escape from Hla-B27–Restricted Cytotoxic T Lymphocyte Responses

  The Journal of Experimental Medicine · 2001 · https://doi.org/10.1084/jem.193.3.375

• Cellular Immune Responses and Viral Diversity in Individuals Treated during Acute and Early HIV-1 Infection

  The Journal of Experimental Medicine · 2001 · https://doi.org/10.1084/jem.193.2.169

• Evolution and transmission of stable CTL escape mutations in HIV infection

  Nature · 2001 · https://doi.org/10.1038/35085576

• Immune control of HIV-1 after early treatment of acute infection

  Nature · 2000 · https://doi.org/10.1038/35035103

• Late escape from an immunodominant cytotoxic T-lymphocyte response associated with progression to AIDS

  Nature Medicine · 1997 · https://doi.org/10.1038/nm0297-212

• Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection

  Proceedings of the National Academy of Sciences · 1997 · https://doi.org/10.1073/pnas.94.5.1890

• Phenotypic Analysis of Antigen-Specific T Lymphocytes

  Science · 1996 · https://doi.org/10.1126/science.274.5284.94

Current projects

No projects listed.