Fabian J. Theis

Research interests

Publications

• An integrated cell atlas of the lung in health and disease

  Nature Medicine · 2023 · https://doi.org/10.1038/s41591-023-02327-2

• A Python library for probabilistic analysis of single-cell omics data

  Nature Biotechnology · 2022 · https://doi.org/10.1038/s41587-021-01206-w

• RNA velocity—current challenges and future perspectives

  Molecular Systems Biology · 2021 · https://doi.org/10.15252/msb.202110282

• Mapping single-cell data to reference atlases by transfer learning

  Nature Biotechnology · 2021 · https://doi.org/10.1038/s41587-021-01001-7

• Swarm Learning for decentralized and confidential clinical machine learning

  Nature · 2021 · https://doi.org/10.1038/s41586-021-03583-3

• SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis

  Cell · 2021 · https://doi.org/10.1016/j.cell.2021.11.033

• SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

  Cell · 2020 · 10.1016/j.cell.2020.04.035

• Generalizing RNA velocity to transient cell states through dynamical modeling

  Nature Biotechnology · 2020 · https://doi.org/10.1038/s41587-020-0591-3

• LifeTime and improving European healthcare through cell-based interceptive medicine

  Nature · 2020 · https://doi.org/10.1038/s41586-020-2715-9

• Inhibition of LTβR signalling activates WNT-induced regeneration in lung

  Nature · 2020 · https://doi.org/10.1038/s41586-020-2882-8

• Eleven grand challenges in single-cell data science

  Genome biology · 2020 · 10.1186/s13059-020-1926-6

• A cellular census of human lungs identifies novel cell states in health and in asthma

  Nature Medicine · 2019 · 10.1038/s41591-019-0468-5

• The Human Lung Cell Atlas: A High-Resolution Reference Map of the Human Lung in Health and Disease

  American Journal of Respiratory Cell and Molecular Biology · 2019 · https://doi.org/10.1165/rcmb.2018-0416tr

• Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

  Nature Communications · 2019 · https://doi.org/10.1038/s41467-019-10461-0

• Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations

  Cell stem cell · 2015 · https://doi.org/10.1016/j.stem.2015.04.004

• Computational analysis of cell-to-cell heterogeneity in single-cell RNA-sequencing data reveals hidden subpopulations of cells

  Nature Biotechnology · 2015 · 10.1038/nbt.3102

• Gender-specific pathway differences in the human serum metabolome

  Metabolomics · 2015 · https://doi.org/10.1007/s11306-015-0829-0

• An atlas of genetic influences on human blood metabolites

  Nature Genetics · 2014 · https://doi.org/10.1038/ng.2982

• The dynamic range of the human metabolome revealed by challenges

  The FASEB Journal · 2012 · https://doi.org/10.1096/fj.11-198093

• Gaussian graphical modeling reconstructs pathway reactions from high-throughput metabolomics data

  BMC Systems Biology · 2011 · https://doi.org/10.1186/1752-0509-5-21

• Discovery of Sexual Dimorphisms in Metabolic and Genetic Biomarkers

  PLoS Genetics · 2011 · https://doi.org/10.1371/journal.pgen.1002215

Current projects

No projects listed.