Jan Bornschein

Research interests

Publications

• Management of epithelial precancerous conditions and early neoplasia of the stomach (MAPS III): European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter and Microbiota Study Group (EHMSG) and European Society of Pathology (ESP) Guideline update 2025

  Endoscopy · 2025 · https://doi.org/10.1055/a-2529-5025

• Helicobacter pylori antibiotic resistance: a global challenge in search of solutions

  Gut · 2025 · 10.1136/gutjnl-2025-335523

• The Role of Microbiota in Gastrointestinal Cancer and Cancer Treatment: Chance or Curse?

  Cellular and Molecular Gastroenterology and Hepatology · 2021 · 10.1016/j.jcmgh.2021.08.013

• Identification of Subtypes of Barrett’s Esophagus and Esophageal Adenocarcinoma Based on DNA Methylation Profiles and Integration of Transcriptome and Genome Data

  Gastroenterology · 2020 · 10.1053/j.gastro.2020.01.044

• A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals

  Nature Immunology · 2020 · https://doi.org/10.1038/s41590-020-0770-x

• S3-Leitlinie Magenkarzinom – Diagnostik und Therapie der Adenokarzinome des Magens und des ösophagogastralen Übergangs – Langversion 2.0 – August 2019. AWMF-Registernummer: 032/009OL

  Zeitschrift für Gastroenterologie · 2019 · 10.1055/a-1018-2516

• Identification of Prognostic Phenotypes of Esophageal Adenocarcinoma in 2 Independent Cohorts

  Gastroenterology · 2018 · 10.1053/j.gastro.2018.08.036

• Multicentre cohort study to define and validate pathological assessment of response to neoadjuvant therapy in oesophagogastric adenocarcinoma

  British journal of surgery · 2017 · 10.1002/bjs.10627

• Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance

  Nature Genetics · 2016 · https://doi.org/10.1038/ng.3659

• Whole-genome sequencing provides new insights into the clonal architecture of Barrett's esophagus and esophageal adenocarcinoma

  Nature Genetics · 2015 · https://doi.org/10.1038/ng.3357

• Characterization and prognosis of patients with hepatocellular carcinoma (HCC) in the non-cirrhotic liver

  BMC Gastroenterology · 2014 · https://doi.org/10.1186/1471-230x-14-117

• Different antibiotic susceptibility between antrum and corpus of the stomach, a possible reason for treatment failure ofHelicobacter pyloriinfection

  World Journal of Gastroenterology · 2014 · 10.3748/wjg.v20.i43.16245

• Antibiotic susceptibility of Helicobacter pylori in central Germany and its relationship with the number of eradication therapies

  European Journal of Gastroenterology & Hepatology · 2013 · 10.1097/meg.0b013e3283643491

• Serological assessment of gastric mucosal atrophy in gastric cancer

  BMC Gastroenterology · 2012 · 10.1186/1471-230x-12-10

• Gastric carcinogenesis

  Langenbeck s Archives of Surgery · 2011 · 10.1007/s00423-011-0810-y

• S3-Leitlinie „Magenkarzinom” -

  Zeitschrift für Gastroenterologie · 2011 · 10.1055/s-0031-1273201

• Lack of association between gene polymorphisms of Angiotensin converting enzyme, Nod-like receptor 1, Toll-like receptor 4, FAS/FASL and the presence of Helicobacter pylori-induced premalignant gastric lesions and gastric cancer in Caucasians

  BMC Medical Genetics · 2011 · 10.1186/1471-2350-12-112

• H. pylori Infection Is a Key Risk Factor for Proximal Gastric Cancer

  Digestive Diseases and Sciences · 2010 · 10.1007/s10620-010-1351-x

• S3-Leitlinie „Helicobacter pylori und gastroduodenale Ulkuskrankheit” der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten (DGVS)

  Zeitschrift für Gastroenterologie · 2009 · https://doi.org/10.1055/s-0028-1109062

• Hepatocellular Carcinoma – Epidemiological Trends and Risk Factors

  Digestive Diseases · 2009 · https://doi.org/10.1159/000218339

• Evolution of the Diffuse Neuroendocrine System – Clear Cells and Cloudy Origins

  Neuroendocrinology · 2006 · 10.1159/000096997

Current projects

No projects listed.