Jonas Frisén

Research interests

Publications

• Spatial deconvolution of HER2-positive breast cancer delineates tumor-associated cell type interactions

  Nature Communications · 2021 · https://doi.org/10.1038/s41467-021-26271-2

• Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin

  Nature Genetics · 2021 · https://doi.org/10.1038/s41588-021-00818-x

• High-definition spatial transcriptomics for in situ tissue profiling

  Nature Methods · 2019 · https://doi.org/10.1038/s41592-019-0548-y

• Human Adult Neurogenesis: Evidence and Remaining Questions

  Cell stem cell · 2018 · https://doi.org/10.1016/j.stem.2018.04.004

• Cardiomyocyte Regeneration

  Circulation · 2017 · 10.1161/circulationaha.117.029343

• The Lifespan and Turnover of Microglia in the Human Brain

  Cell Reports · 2017 · 10.1016/j.celrep.2017.07.004

• Visualization and analysis of gene expression in tissue sections by spatial transcriptomics

  Science · 2016 · https://doi.org/10.1126/science.aaf2403

• Dynamics of Cell Generation and Turnover in the Human Heart

  Cell · 2015 · https://doi.org/10.1016/j.cell.2015.05.026

• Dynamics of Oligodendrocyte Generation and Myelination in the Human Brain

  Cell · 2014 · 10.1016/j.cell.2014.10.011

• Neurogenesis in the Striatum of the Adult Human Brain

  Cell · 2014 · https://doi.org/10.1016/j.cell.2014.01.044

• Dynamics of Hippocampal Neurogenesis in Adult Humans

  Cell · 2013 · https://doi.org/10.1016/j.cell.2013.05.002

• A Pericyte Origin of Spinal Cord Scar Tissue

  Science · 2011 · https://doi.org/10.1126/science.1203165

• Origin of New Glial Cells in Intact and Injured Adult Spinal Cord

  Cell stem cell · 2010 · 10.1016/j.stem.2010.07.014

• Evidence for Cardiomyocyte Renewal in Humans

  Science · 2009 · https://doi.org/10.1126/science.1164680

• Adipocyte Turnover: Relevance to Human Adipose Tissue Morphology

  Diabetes · 2009 · 10.2337/db09-0942

• Dissociation of EphB2 Signaling Pathways Mediating Progenitor Cell Proliferation and Tumor Suppression

  Cell · 2009 · https://doi.org/10.1016/j.cell.2009.08.048

• Dynamics of fat cell turnover in humans

  Nature · 2008 · https://doi.org/10.1038/nature06902

• Spinal Cord Injury Reveals Multilineage Differentiation of Ependymal Cells

  PLoS Biology · 2008 · https://doi.org/10.1371/journal.pbio.0060182

• Human Neuroblasts Migrate to the Olfactory Bulb via a Lateral Ventricular Extension

  Science · 2007 · https://doi.org/10.1126/science.1136281

• Retrospective Birth Dating of Cells in Humans

  Cell · 2005 · 10.1016/j.cell.2005.04.028

• Allodynia limits the usefulness of intraspinal neural stem cell grafts; directed differentiation improves outcome

  Nature Neuroscience · 2005 · https://doi.org/10.1038/nn1405

• Evidence for neurogenesis in the adult mammalian substantia nigra

  Proceedings of the National Academy of Sciences · 2003 · 10.1073/pnas.1131955100

• Genetic Analysis of Ephrin-A2 and Ephrin-A5 Shows Their Requirement in Multiple Aspects of Retinocollicular Mapping

  Neuron · 2000 · 10.1016/s0896-6273(00)81060-0

• Generalized Potential of Adult Neural Stem Cells

  Science · 2000 · https://doi.org/10.1126/science.288.5471.1660

• Identification of a Neural Stem Cell in the Adult Mammalian Central Nervous System

  Cell · 1999 · https://doi.org/10.1016/s0092-8674(00)80956-3

• Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development.

  Genes & Development · 1997 · 10.1101/gad.11.8.973

• Renal agenesis and the absence of enteric neurons in mice lacking GDNF

  Nature · 1996 · https://doi.org/10.1038/382070a0

• Differential expression of mRNAs for neurotrophins and their receptors after axotomy of the sciatic nerve.

  The Journal of Cell Biology · 1993 · https://doi.org/10.1083/jcb.123.2.455

Current projects

No projects listed.