Kimberly Martinod

Research interests

Publications

• Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity

  Nature Communications · 2021 · https://doi.org/10.1038/s41467-021-24360-w

• Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19

  Nature reviews. Immunology · 2021 · https://doi.org/10.1038/s41577-021-00536-9

• Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages

  Cell Research · 2021 · https://doi.org/10.1038/s41422-020-00455-9

• Increased neutrophil extracellular trap formation promotes thrombosis in myeloproliferative neoplasms

  Science Translational Medicine · 2018 · https://doi.org/10.1126/scitranslmed.aan8292

• Citrullinated histone H3, a biomarker of neutrophil extracellular trap formation, predicts the risk of venous thromboembolism in cancer patients

  Journal of Thrombosis and Haemostasis · 2018 · https://doi.org/10.1111/jth.13951

• Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

  Nature Chemical Biology · 2015 · https://doi.org/10.1038/nchembio.1735

• Diabetes primes neutrophils to undergo NETosis, which impairs wound healing

  Nature Medicine · 2015 · https://doi.org/10.1038/nm.3887

• P-selectin promotes neutrophil extracellular trap formation in mice

  Blood · 2015 · https://doi.org/10.1182/blood-2015-01-624023

• Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice

  Proceedings of the National Academy of Sciences · 2013 · https://doi.org/10.1073/pnas.1301059110

• Thrombosis: tangled up in NETs

  Blood · 2013 · https://doi.org/10.1182/blood-2013-10-463646

• Elevated Levels of Circulating DNA and Chromatin Are Independently Associated With Severe Coronary Atherosclerosis and a Prothrombotic State

  Arteriosclerosis Thrombosis and Vascular Biology · 2013 · https://doi.org/10.1161/atvbaha.113.301627

• Extracellular DNA traps are associated with the pathogenesis of TRALI in humans and mice

  Blood · 2012 · https://doi.org/10.1182/blood-2012-01-405183

• Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis

  Proceedings of the National Academy of Sciences · 2012 · https://doi.org/10.1073/pnas.1200419109

• Neutrophil extracellular traps promote deep vein thrombosis in mice

  Journal of Thrombosis and Haemostasis · 2011 · https://doi.org/10.1111/j.1538-7836.2011.04544.x

• Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions

  The Journal of Experimental Medicine · 2008 · https://doi.org/10.1084/jem.20081880

Current projects

No projects listed.