Hinrich Abken

Researcher Next ID · RN-028830

Researcher · Medicine

Berlin, Chile

Not currently recruitingFunding unknown

Research interests

Medicine

Immunology and Microbiology

Biochemistry, Genetics and Molecular Biology

CAR-T cell therapy research

Immune Cell Function and Interaction

Immunotherapy and Immune Responses

Monoclonal and Polyclonal Antibodies Research

Virus-based gene therapy research

CAR T Cells Releasing IL-18 Convert to T-Bethigh FoxO1low Effectors that Exhibit Augmented Activity against Advanced Solid Tumors
Cell Reports · 2017 · https://doi.org/10.1016/j.celrep.2017.11.063
TRUCKs: the fourth generation of CARs
Expert Opinion on Biological Therapy · 2015 · https://doi.org/10.1517/14712598.2015.1046430
Of CAR s and TRUCK s: chimeric antigen receptor ( CAR ) T cells engineered with an inducible cytokine to modulate the tumor stroma
Immunological Reviews · 2013 · https://doi.org/10.1111/imr.12125
IL-12 Release by Engineered T Cells Expressing Chimeric Antigen Receptors Can Effectively Muster an Antigen-Independent Macrophage Response on Tumor Cells That Have Shut Down Tumor Antigen Expression
Cancer Research · 2011 · https://doi.org/10.1158/0008-5472.can-11-0103
Tumor-Specific T Cell Activation by Recombinant Immunoreceptors: CD3ζ Signaling and CD28 Costimulation Are Simultaneously Required for Efficient IL-2 Secretion and Can Be Integrated Into One Combined CD28/CD3ζ Signaling Receptor Molecule
The Journal of Immunology · 2001 · https://doi.org/10.4049/jimmunol.167.11.6123

No projects listed.