Frank Leypoldt

Research interests

Publications

• Update on the diagnosis and treatment of neuromyelitis optica spectrum disorders (NMOSD) – revised recommendations of the Neuromyelitis Optica Study Group (NEMOS). Part II: Attack therapy and long-term management

  Journal of Neurology · 2023 · 10.1007/s00415-023-11910-z

• Updated Diagnostic Criteria for Paraneoplastic Neurologic Syndromes

  Neurology Neuroimmunology & Neuroinflammation · 2021 · https://doi.org/10.1212/nxi.0000000000001014

• Rituximab Treatment and Long-term Outcome of Patients With Autoimmune Encephalitis

  Neurology Neuroimmunology & Neuroinflammation · 2021 · 10.1212/nxi.0000000000001088

• Proteome profiling in cerebrospinal fluid reveals novel biomarkers of Alzheimer's disease

  Molecular Systems Biology · 2020 · 10.15252/msb.20199356

• Low-Avidity CD4+ T Cell Responses to SARS-CoV-2 in Unexposed Individuals and Humans with Severe COVID-19

  Immunity · 2020 · 10.1016/j.immuni.2020.11.016

• An update on anti-NMDA receptor encephalitis for neurologists and psychiatrists: mechanisms and models

  The Lancet Neurology · 2019 · https://doi.org/10.1016/s1474-4422(19)30244-3

• Mechanisms of Autoantibody-Induced Pathology

  Frontiers in Immunology · 2017 · 10.3389/fimmu.2017.00603

• Prognostic relevance of MOG antibodies in children with an acquired demyelinating syndrome

  Neurology · 2017 · 10.1212/wnl.0000000000004312

• A clinical approach to diagnosis of autoimmune encephalitis

  The Lancet Neurology · 2016 · https://doi.org/10.1016/s1474-4422(15)00401-9

• The clinical spectrum of Caspr2 antibody–associated disease

  Neurology · 2016 · 10.1212/wnl.0000000000002917

• Structural Hippocampal Damage Following Anti-N-Methyl-D-Aspartate Receptor Encephalitis

  Biological Psychiatry · 2015 · 10.1016/j.biopsych.2015.02.024

• Encephalitis and AMPA receptor antibodies

  Neurology · 2015 · 10.1212/wnl.0000000000001682

• Autoimmune encephalopathies

  Annals of the New York Academy of Sciences · 2014 · https://doi.org/10.1111/nyas.12553

• Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice

  Brain · 2014 · 10.1093/brain/awu310

• Autoimmune encephalitis as differential diagnosis of infectious encephalitis

  Current Opinion in Neurology · 2014 · 10.1097/wco.0000000000000087

• Overlapping demyelinating syndromes and anti–N‐methyl‐D‐aspartate receptor encephalitis

  Annals of Neurology · 2014 · 10.1002/ana.24117

• Investigations on CXCL13 in Anti– N -Methyl- D -Aspartate Receptor Encephalitis

  JAMA Neurology · 2014 · 10.1001/jamaneurol.2014.2956

• Herpes simplex virus encephalitis is a trigger of brain autoimmunity

  Annals of Neurology · 2013 · https://doi.org/10.1002/ana.24083

• Antibody titres at diagnosis and during follow-up of anti-NMDA receptor encephalitis: a retrospective study

  The Lancet Neurology · 2013 · 10.1016/s1474-4422(13)70282-5

• Functional and structural brain changes in anti–N‐methyl‐D‐aspartate receptor encephalitis

  Annals of Neurology · 2013 · 10.1002/ana.23932

• Herpes simplex virus–1 encephalitis can trigger anti-NMDA receptor encephalitis: Case report

  Neurology · 2013 · 10.1212/wnl.0b013e3182a9f531

• Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke

  Blood · 2012 · 10.1182/blood-2012-02-412726

• Fluorodeoxyglucose positron emission tomography in anti-N-methyl-D-aspartate receptor encephalitis: distinct pattern of disease

  Journal of Neurology Neurosurgery & Psychiatry · 2012 · 10.1136/jnnp-2011-301969

• Leitlinien für Diagnostik und Therapie in der Neurologie

  · 2012 · 10.1055/b-002-37755

• Temporal and Spatial Dynamics of Cerebral Immune Cell Accumulation in Stroke

  Stroke · 2009 · 10.1161/strokeaha.108.534503

Current projects

No projects listed.