Tony R. Merriman

Research interests

Publications

• Assessing the Causal Relationships Between Insulin Resistance and Hyperuricemia and Gout Using Bidirectional Mendelian Randomization

  Arthritis & Rheumatology · 2021 · 10.1002/art.41779

• Serum Metabolomics Identifies Dysregulated Pathways and Potential Metabolic Biomarkers for Hyperuricemia and Gout

  Arthritis & Rheumatology · 2021 · https://doi.org/10.1002/art.41733

• The ABCG2 Q141K hyperuricemia and gout associated variant illuminates the physiology of human urate excretion

  Nature Communications · 2020 · 10.1038/s41467-020-16525-w

• Mouse models for human hyperuricaemia: a critical review

  Nature Reviews Rheumatology · 2019 · 10.1038/s41584-019-0222-x

• No causal effects of serum urate levels on the risk of chronic kidney disease: A Mendelian randomization study

  PLoS Medicine · 2019 · 10.1371/journal.pmed.1002725

• Hyperuricemia, Acute and Chronic Kidney Disease, Hypertension, and Cardiovascular Disease: Report of a Scientific Workshop Organized by the National Kidney Foundation

  American Journal of Kidney Diseases · 2018 · https://doi.org/10.1053/j.ajkd.2017.12.009

• An update on the genetics of hyperuricaemia and gout

  Nature Reviews Rheumatology · 2018 · 10.1038/s41584-018-0004-x

• Evaluation of the diet wide contribution to serum urate levels: meta-analysis of population based cohorts

  BMJ · 2018 · 10.1136/bmj.k3951

• Relationship between serum urate concentration and clinically evident incident gout: an individual participant data analysis

  Annals of the Rheumatic Diseases · 2018 · https://doi.org/10.1136/annrheumdis-2017-212288

• Risk factors for cryptorchidism

  Nature Reviews Urology · 2017 · 10.1038/nrurol.2017.90

• Hypodontia: An Update on Its Etiology, Classification, and Clinical Management

  BioMed Research International · 2017 · 10.1155/2017/9378325

• Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci

  Circulation Research · 2016 · https://doi.org/10.1161/circresaha.116.308765

• GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes

  Annals of the Rheumatic Diseases · 2016 · 10.1136/annrheumdis-2016-209632

• Gout

  The Lancet · 2016 · https://doi.org/10.1016/s0140-6736(16)00346-9

• Modulation of Genetic Associations with Serum Urate Levels by Body-Mass-Index in Humans

  PLoS ONE · 2015 · https://doi.org/10.1371/journal.pone.0119752

• An update on the genetic architecture of hyperuricemia and gout

  Arthritis Research & Therapy · 2015 · https://doi.org/10.1186/s13075-015-0609-2

• The global burden of gout: estimates from the Global Burden of Disease 2010 study

  Annals of the Rheumatic Diseases · 2014 · 10.1136/annrheumdis-2013-204647

• Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013

  The Lancet · 2014 · https://doi.org/10.1016/s0140-6736(14)60460-8

• Twenty-eight loci that influence serum urate levels: analysis of association with gout

  Annals of the Rheumatic Diseases · 2014 · 10.1136/annrheumdis-2014-205877

• The genetic basis of hyperuricaemia and gout

  Joint Bone Spine · 2010 · https://doi.org/10.1016/j.jbspin.2010.02.027

• Association analysis of the interleukin 17A gene in Caucasian rheumatoid arthritis patients from Norway and New Zealand

  Lara D. Veeken · 2009 · 10.1093/rheumatology/ken512

• Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20

  Nature Genetics · 2009 · 10.1038/ng.396

• Confirmation of association of IRGM and NCF4 with ileal Crohn's disease in a population-based cohort

  Genes and Immunity · 2008 · 10.1038/gene.2008.49

• Evidence for an influence of chemokine ligand 3-like 1 (CCL3L1) gene copy number on susceptibility to rheumatoid arthritis

  Annals of the Rheumatic Diseases · 2007 · 10.1136/ard.2007.075028

• The genetically isolated populations of Finland and Sardinia may not be a panacea for linkage disequilibrium mapping of common disease genes

  Nature Genetics · 2000 · https://doi.org/10.1038/77091

• Cloning and characterization of pvdS, a gene required for pyoverdine synthesis in Pseudomonas aeruginosa: PvdS is probably an alternative sigma factor

  Journal of Bacteriology · 1995 · 10.1128/jb.177.10.2744-2750.1995

Current projects

No projects listed.