Lawrence S. Young

Research interests

Publications

• Epstein–Barr virus: more than 50 years old and still providing surprises

  Nature reviews. Cancer · 2016 · https://doi.org/10.1038/nrc.2016.92

• The role of the EBV-encoded latent membrane proteins LMP1 and LMP2 in the pathogenesis of nasopharyngeal carcinoma (NPC)

  Seminars in Cancer Biology · 2012 · https://doi.org/10.1016/j.semcancer.2012.01.004

• Epstein-Barr virus-encoded EBNA1 inhibits the canonical NF-κB pathway in carcinoma cells by inhibiting IKK phosphorylation

  Molecular Cancer · 2010 · https://doi.org/10.1186/1476-4598-9-1

• Expression of the Epstein-Barr Virus-Encoded Epstein-Barr Virus Nuclear Antigen 1 in Hodgkin's Lymphoma Cells Mediates Up-Regulation of CCL20 and the Migration of Regulatory T Cells

  American Journal Of Pathology · 2008 · https://doi.org/10.2353/ajpath.2008.070845

• The natural history of cervical HPV infection: unresolved issues

  Nature reviews. Cancer · 2006 · https://doi.org/10.1038/nrc2050

• Viral gene therapy strategies: from basic science to clinical application

  The Journal of Pathology · 2005 · https://doi.org/10.1002/path.1896

• Epstein–Barr virus: 40 years on

  Nature reviews. Cancer · 2004 · https://doi.org/10.1038/nrc1452

• Epstein–Barr virus and oncogenesis: from latent genes to tumours

  Oncogene · 2003 · https://doi.org/10.1038/sj.onc.1206556

• Natural history of cervical human papillomavirus infection in young women: a longitudinal cohort study

  The Lancet · 2001 · https://doi.org/10.1016/s0140-6736(00)04956-4

• Molecular Evolution of the Metaplasia-Dysplasia-Adenocarcinoma Sequence in the Esophagus

  American Journal Of Pathology · 1999 · https://doi.org/10.1016/s0002-9440(10)65346-1

• Activation of the p38 Mitogen-activated Protein Kinase Pathway by Epstein-Barr Virus-encoded Latent Membrane Protein 1 Coregulates Interleukin-6 and Interleukin-8 Production

  Journal of Biological Chemistry · 1999 · https://doi.org/10.1074/jbc.274.23.16085

• Epstein-Barr virus latency in blood mononuclear cells: analysis of viral gene transcription during primary infection and in the carrier state

  Journal of Virology · 1994 · https://doi.org/10.1128/jvi.68.11.7374-7385.1994

• Epstein-Barr virus and Hodgkin's disease: transcriptional analysis of virus latency in the malignant cells.

  The Journal of Experimental Medicine · 1993 · https://doi.org/10.1084/jem.177.2.339

• Epstein-Barr virus latent gene transcription in nasopharyngeal carcinoma cells: coexpression of EBNA1, LMP1, and LMP2 transcripts

  Journal of Virology · 1992 · https://doi.org/10.1128/jvi.66.5.2689-2697.1992

• Epstein-Barr virus (EBV)-associated lymphoproliferative disease in the SCID mouse model: implications for the pathogenesis of EBV-positive lymphomas in man.

  The Journal of Experimental Medicine · 1991 · https://doi.org/10.1084/jem.173.1.147

• Expression of Epstein-Barr virus latent gene products in tumour cells of Hodgkin's disease

  The Lancet · 1991 · https://doi.org/10.1016/0140-6736(91)90943-j

• Guidelines for the Use of Antimicrobial Agents in Neutropenic Patients with Unexplained Fever--Reply

  The Journal of Infectious Diseases · 1991 · https://doi.org/10.1093/infdis/163.1.202

• Epstein–Barr virus latent membrane protein inhibits human epithelial cell differentiation

  Nature · 1990 · https://doi.org/10.1038/344777a0

• From the Infectious Diseases Society of America: Guidelines for the Use of Antimicrobial Agents in Neutropenic Patients with Unexplained Fever

  The Journal of Infectious Diseases · 1990 · https://doi.org/10.1093/infdis/161.3.381

• Epstein-Barr virus types 1 and 2 differ in their EBNA-3A, EBNA-3B, and EBNA-3C genes

  Journal of Virology · 1990 · https://doi.org/10.1128/jvi.64.9.4084-4092.1990

• Expression of Epstein–Barr Virus Transformation–Associated Genes in Tissues of Patients with EBV Lymphoproliferative Disease

  New England Journal of Medicine · 1989 · https://doi.org/10.1056/nejm198910193211604

• Epstein--Barr Virus Gene Expression in Nasopharyngeal Carcinoma

  Journal of General Virology · 1988 · https://doi.org/10.1099/0022-1317-69-5-1051

• Tumor necrosis factor, alone or in combination with IL-2, but not IFN-gamma, is associated with macrophage killing of Mycobacterium avium complex.

  The Journal of Immunology · 1988 · https://doi.org/10.4049/jimmunol.140.9.3006

• Influence of the Epstein-Barr virus nuclear antigen EBNA 2 on the growth phenotype of virus-transformed B cells

  Journal of Virology · 1987 · https://doi.org/10.1128/jvi.61.5.1310-1317.1987

• Differences in B cell growth phenotype reflect novel patterns of Epstein‐Barr virus latent gene expression in Burkitt's lymphoma cells.

  The EMBO Journal · 1987 · https://doi.org/10.1002/j.1460-2075.1987.tb02568.x

Current projects

No projects listed.