Harald Hampel

Research interests

Publications

• Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum

  JAMA Neurology · 2022 · https://doi.org/10.1001/jamaneurol.2021.5216

• The Amyloid-β Pathway in Alzheimer’s Disease

  Molecular Psychiatry · 2021 · https://doi.org/10.1038/s41380-021-01249-0

• The β-Secretase BACE1 in Alzheimer’s Disease

  Biological Psychiatry · 2020 · 10.1016/j.biopsych.2020.02.001

• Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study

  The Lancet Neurology · 2019 · https://doi.org/10.1016/s1474-4422(19)30283-2

• Blood-based biomarkers for Alzheimer disease: mapping the road to the clinic

  Nature Reviews Neurology · 2018 · https://doi.org/10.1038/s41582-018-0079-7

• Sex differences in Alzheimer disease — the gateway to precision medicine

  Nature Reviews Neurology · 2018 · 10.1038/s41582-018-0032-9

• Analysis of shared heritability in common disorders of the brain

  Science · 2018 · https://doi.org/10.1126/science.aap8757

• The cholinergic system in the pathophysiology and treatment of Alzheimer’s disease

  Brain · 2018 · https://doi.org/10.1093/brain/awy132

• Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

  JAMA Psychiatry · 2017 · https://doi.org/10.1001/jamapsychiatry.2017.3391

• Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

  Nature Genetics · 2017 · https://doi.org/10.1038/ng.3916

• A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers

  Neurology · 2016 · 10.1212/wnl.0000000000002923

• Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria

  Alzheimer s & Dementia · 2016 · 10.1016/j.jalz.2016.02.002

• Prevalence and prognosis of Alzheimer’s disease at the mild cognitive impairment stage

  Brain · 2015 · https://doi.org/10.1093/brain/awv029

• Prevalence of Cerebral Amyloid Pathology in Persons Without Dementia

  JAMA · 2015 · 10.1001/jama.2015.4668

• A novel Alzheimer disease locus located near the gene encoding tau protein

  Molecular Psychiatry · 2015 · https://doi.org/10.1038/mp.2015.23

• Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria

  The Lancet Neurology · 2014 · https://doi.org/10.1016/s1474-4422(14)70090-0

• The EADC‐ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance: Evidence of validity

  Alzheimer s & Dementia · 2014 · https://doi.org/10.1016/j.jalz.2014.05.1756

• Variant of TREM2 Associated with the Risk of Alzheimer's Disease

  New England Journal of Medicine · 2012 · https://doi.org/10.1056/nejmoa1211103

• Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

  Nature Genetics · 2011 · https://doi.org/10.1038/ng.803

• Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease

  PLoS ONE · 2010 · 10.1371/journal.pone.0013950

• Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

  Nature Reviews Neurology · 2010 · 10.1038/nrneurol.2010.4

• Revising the definition of Alzheimer's disease: a new lexicon

  The Lancet Neurology · 2010 · 10.1016/s1474-4422(10)70223-4

• Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

  Nature Genetics · 2009 · https://doi.org/10.1038/ng.440

• Mild cognitive impairment

  The Lancet · 2006 · https://doi.org/10.1016/s0140-6736(06)68542-5

• Automated cortical thickness measurements from MRI can accurately separate Alzheimer's patients from normal elderly controls

  Neurobiology of Aging · 2006 · https://doi.org/10.1016/j.neurobiolaging.2006.09.013

• Classifying brain states and determining the discriminating activation patterns: Support Vector Machine on functional MRI data

  NeuroImage · 2005 · 10.1016/j.neuroimage.2005.06.070

• Focal Decline of Cortical Thickness in Alzheimer's Disease Identified by Computational Neuroanatomy

  Cerebral Cortex · 2004 · https://doi.org/10.1093/cercor/bhh200

• CSF markers for incipient Alzheimer's disease

  The Lancet Neurology · 2003 · 10.1016/s1474-4422(03)00530-1

Current projects

No projects listed.