Frank J. Steemers

Research interests

Publications

• A human cell atlas of fetal gene expression

  Science · 2020 · https://doi.org/10.1126/science.aba7721

• A human cell atlas of fetal chromatin accessibility

  Science · 2020 · 10.1126/science.aba7612

• Droplet-based combinatorial indexing for massive-scale single-cell chromatin accessibility

  Nature Biotechnology · 2019 · 10.1038/s41587-019-0147-6

• The single-cell transcriptional landscape of mammalian organogenesis

  Nature · 2019 · https://doi.org/10.1038/s41586-019-0969-x

• Massively multiplex chemical transcriptomics at single-cell resolution

  Science · 2019 · 10.1126/science.aax6234

• Transcriptomic and morphophysiological evidence for a specialized human cortical GABAergic cell type

  Nature Neuroscience · 2018 · 10.1038/s41593-018-0205-2

• Highly scalable generation of DNA methylation profiles in single cells

  Nature Biotechnology · 2018 · 10.1038/nbt.4112

• The cis-regulatory dynamics of embryonic development at single-cell resolution

  Nature · 2018 · 10.1038/nature25981

• Cicero Predicts cis-Regulatory DNA Interactions from Single-Cell Chromatin Accessibility Data

  Molecular Cell · 2018 · https://doi.org/10.1016/j.molcel.2018.06.044

• A Single-Cell Atlas of In Vivo Mammalian Chromatin Accessibility

  Cell · 2018 · 10.1016/j.cell.2018.06.052

• Joint profiling of chromatin accessibility and gene expression in thousands of single cells

  Science · 2018 · https://doi.org/10.1126/science.aau0730

• Massively multiplex single-cell Hi-C

  Nature Methods · 2017 · 10.1038/nmeth.4155

• Comprehensive single-cell transcriptional profiling of a multicellular organism

  Science · 2017 · https://doi.org/10.1126/science.aam8940

• Sequencing thousands of single-cell genomes with combinatorial indexing

  Nature Methods · 2017 · 10.1038/nmeth.4154

• Multiplex single-cell profiling of chromatin accessibility by combinatorial cellular indexing

  Science · 2015 · 10.1126/science.aab1601

• Haplotype-resolved whole-genome sequencing by contiguity-preserving transposition and combinatorial indexing

  Nature Genetics · 2014 · 10.1038/ng.3119

• Whole genome genotyping technologies on the BeadArray™ platform

  Biotechnology Journal · 2007 · 10.1002/biot.200600213

• High-resolution genomic profiling of chromosomal aberrations using Infinium whole-genome genotyping

  Genome Research · 2006 · https://doi.org/10.1101/gr.5402306

• Whole-genome genotyping with the single-base extension assay

  Nature Methods · 2005 · https://doi.org/10.1038/nmeth842

• A genome-wide scalable SNP genotyping assay using microarray technology

  Nature Genetics · 2005 · 10.1038/ng1547

• High-throughput SNP genotyping on universal bead arrays

  Mutation research. Fundamental and molecular mechanisms of mutagenesis · 2005 · 10.1016/j.mrfmmm.2004.07.022

• Highly Parallel SNP Genotyping

  Cold Spring Harbor Symposia on Quantitative Biology · 2003 · 10.1101/sqb.2003.68.69

• High-Density Fiber-Optic DNA Random Microsphere Array

  Analytical Chemistry · 2000 · 10.1021/ac0008284

• Screening unlabeled DNA targets with randomly ordered fiber-optic gene arrays

  Nature Biotechnology · 2000 · 10.1038/72006

• New Sensitizer-Modified Calix[4]arenes Enabling Near-UV Excitation of Complexed Luminescent Lanthanide Ions

  Journal of the American Chemical Society · 1995 · 10.1021/ja00142a004

Current projects

No projects listed.