Claudius Werner

Research interests

Publications

• Effects of Liberal vs Restrictive Transfusion Thresholds on Survival and Neurocognitive Outcomes in Extremely Low-Birth-Weight Infants

  JAMA · 2020 · https://doi.org/10.1001/jama.2020.10690

• Efficacy and safety of azithromycin maintenance therapy in primary ciliary dyskinesia (BESTCILIA): a multicentre, double-blind, randomised, placebo-controlled phase 3 trial

  The Lancet Respiratory Medicine · 2020 · 10.1016/s2213-2600(20)30058-8

• Recessive DNAH9 Loss-of-Function Mutations Cause Laterality Defects and Subtle Respiratory Ciliary-Beating Defects

  The American Journal of Human Genetics · 2018 · 10.1016/j.ajhg.2018.10.020

• Evolutionary Proteomics Uncovers Ancient Associations of Cilia with Signaling Pathways

  Developmental Cell · 2017 · 10.1016/j.devcel.2017.11.014

• Primary Ciliary Dyskinesia: An Update on Clinical Aspects, Genetics, Diagnosis, and Future Treatment Strategies

  Frontiers in Pediatrics · 2017 · 10.3389/fped.2017.00135

• European Respiratory Society guidelines for the diagnosis of primary ciliary dyskinesia

  European Respiratory Journal · 2016 · https://doi.org/10.1183/13993003.01090-2016

• DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes

  American Journal of Respiratory Cell and Molecular Biology · 2016 · 10.1165/rcmb.2015-0353oc

• Mutations in PIH1D3 Cause X-Linked Primary Ciliary Dyskinesia with Outer and Inner Dynein Arm Defects

  The American Journal of Human Genetics · 2016 · 10.1016/j.ajhg.2016.11.019

• TTC25 Deficiency Results in Defects of the Outer Dynein Arm Docking Machinery and Primary Ciliary Dyskinesia with Left-Right Body Asymmetry Randomization

  The American Journal of Human Genetics · 2016 · 10.1016/j.ajhg.2016.06.014

• Diagnosis and management of primary ciliary dyskinesia

  Cilia · 2015 · 10.1186/s13630-014-0011-8

• Mutations in CCNO result in congenital mucociliary clearance disorder with reduced generation of multiple motile cilia

  Nature Genetics · 2014 · 10.1038/ng.2961

• MCIDAS mutations result in a mucociliary clearance disorder with reduced generation of multiple motile cilia

  Nature Communications · 2014 · 10.1038/ncomms5418

• Ciliary beat pattern and frequency in genetic variants of primary ciliary dyskinesia

  European Respiratory Journal · 2014 · 10.1183/09031936.00052014

• CCDC151 Mutations Cause Primary Ciliary Dyskinesia by Disruption of the Outer Dynein Arm Docking Complex Formation

  The American Journal of Human Genetics · 2014 · 10.1016/j.ajhg.2014.08.005

• Mutations in SPAG1 Cause Primary Ciliary Dyskinesia Associated with Defective Outer and Inner Dynein Arms

  The American Journal of Human Genetics · 2013 · 10.1016/j.ajhg.2013.07.025

• ARMC4 Mutations Cause Primary Ciliary Dyskinesia with Randomization of Left/Right Body Asymmetry

  The American Journal of Human Genetics · 2013 · 10.1016/j.ajhg.2013.06.009

• The nexin-dynein regulatory complex subunit DRC1 is essential for motile cilia function in algae and humans

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2533

• ZMYND10 Is Mutated in Primary Ciliary Dyskinesia and Interacts with LRRC6

  The American Journal of Human Genetics · 2013 · 10.1016/j.ajhg.2013.06.007

• DYX1C1 is required for axonemal dynein assembly and ciliary motility

  Nature Genetics · 2013 · 10.1038/ng.2707

• CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms

  Nature Genetics · 2012 · 10.1038/ng.2277

• Recessive HYDIN Mutations Cause Primary Ciliary Dyskinesia without Randomization of Left-Right Body Asymmetry

  The American Journal of Human Genetics · 2012 · 10.1016/j.ajhg.2012.08.016

• Mutations of DNAH11 in patients with primary ciliary dyskinesia with normal ciliary ultrastructure

  Thorax · 2011 · 10.1136/thoraxjnl-2011-200301

Current projects

No projects listed.