Steffen Durinck

Research interests

Publications

• The Indian cobra reference genome and transcriptome enables comprehensive identification of venom toxins

  Nature Genetics · 2020 · 10.1038/s41588-019-0559-8

• The GenomeAsia 100K Project enables genetic discoveries across Asia

  Nature · 2019 · 10.1038/s41586-019-1793-z

• An Empirical Approach Leveraging Tumorgrafts to Dissect the Tumor Microenvironment in Renal Cell Carcinoma Identifies Missing Link to Prognostic Inflammatory Factors

  Cancer Discovery · 2018 · 10.1158/2159-8290.cd-17-1246

• CRISPR off-target analysis in genetically engineered rats and mice

  Nature Methods · 2018 · 10.1038/s41592-018-0011-5

• Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations

  Cancer Cell · 2018 · 10.1016/j.ccell.2018.09.010

• Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia

  The Journal of Cell Biology · 2017 · 10.1083/jcb.201612160

• Single-cell RNA sequencing identifies distinct mouse medial ganglionic eminence cell types

  Scientific Reports · 2017 · 10.1038/srep45656

• Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations

  Nature Genetics · 2016 · https://doi.org/10.1038/ng.3520

• Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function

  Nature · 2015 · 10.1038/nature16466

• The BioMart community portal: an innovative alternative to large, centralized data repositories

  Nucleic Acids Research · 2015 · 10.1093/nar/gkv350

• Spectrum of diverse genomic alterations define non–clear cell renal carcinoma subtypes

  Nature Genetics · 2014 · 10.1038/ng.3146

• A comprehensive transcriptional portrait of human cancer cell lines

  Nature Biotechnology · 2014 · 10.1038/nbt.3080

• Oncogenic ERBB3 Mutations in Human Cancers

  Cancer Cell · 2013 · 10.1016/j.ccr.2013.04.012

• Modeling precision treatment of breast cancer

  Genome biology · 2013 · 10.1186/gb-2013-14-10-r110

• Recurrent R-spondin fusions in colon cancer

  Nature · 2012 · https://doi.org/10.1038/nature11282

• Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.2405

• Temporal Dissection of Tumorigenesis in Primary Cancers

  Cancer Discovery · 2011 · 10.1158/2159-8290.cd-11-0028

• Subtype and pathway specific responses to anticancer compounds in breast cancer

  Proceedings of the National Academy of Sciences · 2011 · https://doi.org/10.1073/pnas.1018854108

• Exon-Level Microarray Analyses Identify Alternative Splicing Programs in Breast Cancer

  Molecular Cancer Research · 2010 · 10.1158/1541-7786.mcr-09-0528

• Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

  Nature Protocols · 2009 · https://doi.org/10.1038/nprot.2009.97

• The MYCN oncogene is a direct target of miR-34a

  Oncogene · 2008 · 10.1038/onc.2008.154

• Molecular effectors and modulators of hypericin-mediated cell death in bladder cancer cells

  Oncogene · 2007 · 10.1038/sj.onc.1210825

• BioMart and Bioconductor: a powerful link between biological databases and microarray data analysis

  Computer applications in the biosciences · 2005 · 10.1093/bioinformatics/bti525

• Expression Profiler: next generation--an online platform for analysis of microarray data

  Nucleic Acids Research · 2004 · 10.1093/nar/gkh470

• Versatile Gene-Specific Sequence Tags forArabidopsisFunctional Genomics: Transcript Profiling and Reverse Genetics Applications

  Genome Research · 2004 · 10.1101/gr.2544504

Current projects

No projects listed.