Christian Griesinger

Research interests

Publications

• Oligodendroglial NMDA Receptors Regulate Glucose Import and Axonal Energy Metabolism

  Neuron · 2016 · 10.1016/j.neuron.2016.05.016

• Facing and Overcoming Sensitivity Challenges in Biomolecular NMR Spectroscopy

  Angewandte Chemie International Edition · 2015 · https://doi.org/10.1002/anie.201410653

• Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytes

  Nature Methods · 2014 · 10.1038/nmeth.2773

• Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson’s disease

  Acta Neuropathologica · 2013 · 10.1007/s00401-013-1114-9

• Atomic model of the type III secretion system needle

  Nature · 2012 · 10.1038/nature11079

• Dynamic nuclear polarization at high magnetic fields in liquids

  Progress in Nuclear Magnetic Resonance Spectroscopy · 2011 · https://doi.org/10.1016/j.pnmrs.2011.10.002

• Structural Polymorphism of 441-Residue Tau at Single Residue Resolution

  PLoS Biology · 2009 · https://doi.org/10.1371/journal.pbio.1000034

• Pre‐fibrillar α‐synuclein variants with impaired β‐structure increase neurotoxicity in Parkinson's disease models

  The EMBO Journal · 2009 · 10.1038/emboj.2009.257

• Structure of the human voltage-dependent anion channel

  Proceedings of the National Academy of Sciences · 2008 · 10.1073/pnas.0808115105

• Recognition Dynamics Up to Microseconds Revealed from an RDC-Derived Ubiquitin Ensemble in Solution

  Science · 2008 · https://doi.org/10.1126/science.1157092

• Interaction of α-Synuclein with Divalent Metal Ions Reveals Key Differences: A Link between Structure, Binding Specificity and Fibrillation Enhancement

  Journal of the American Chemical Society · 2006 · 10.1021/ja0618649

• Sites of Tau Important for Aggregation Populate β-Structure and Bind to Microtubules and Polyanions

  Journal of Biological Chemistry · 2005 · 10.1074/jbc.m501565200

• Release of long-range tertiary interactions potentiates aggregation of natively unstructured α-synuclein

  Proceedings of the National Academy of Sciences · 2005 · https://doi.org/10.1073/pnas.0407146102

• Structural characterization of copper(II) binding to α-synuclein: Insights into the bioinorganic chemistry of Parkinson's disease

  Proceedings of the National Academy of Sciences · 2005 · 10.1073/pnas.0407881102

• Model-Free Approach to the Dynamic Interpretation of Residual Dipolar Couplings in Globular Proteins

  Journal of the American Chemical Society · 2001 · 10.1021/ja010002z

• NMR Solution Structure of a Complex of Calmodulin with a Binding Peptide of the Ca2+ Pump,

  Biochemistry · 1999 · https://doi.org/10.1021/bi9908235

• Unitary Control in Quantum Ensembles: Maximizing Signal Intensity in Coherent Spectroscopy

  Science · 1998 · https://doi.org/10.1126/science.280.5362.421

• Direct Measurement of Angles Between Bond Vectors in High-Resolution NMR

  Science · 1997 · 10.1126/science.276.5316.1230

• A general enhancement scheme in heteronuclear multidimensional NMR employing pulsed field gradients

  Journal of Biomolecular NMR · 1994 · https://doi.org/10.1007/bf00175254

• Coherence Selection by Gradients without Signal Attenuation: Application to the Three‐Dimensional HNCO Experiment

  Angewandte Chemie International Edition in English · 1993 · 10.1002/anie.199314891

• Two‐Dimensional NMR Spectroscopy: Background and Overview of the Experiments [New Analytical Methods (36)]

  Angewandte Chemie International Edition in English · 1988 · 10.1002/anie.198804901

• Practical aspects of the E.COSY technique. Measurement of scalar spin-spin coupling constants in peptides

  Journal of Magnetic Resonance (1969) · 1987 · 10.1016/0022-2364(87)90102-8

• Separation of cross-relaxation and J cross-peaks in 2D rotating-frame NMR spectroscopy

  Journal of the American Chemical Society · 1987 · 10.1021/ja00236a063

• Frequency offset effects and their elimination in NMR rotating-frame cross-relaxation spectroscopy

  Journal of Magnetic Resonance (1969) · 1987 · 10.1016/0022-2364(87)90035-7

• Transformation of homonuclear two-dimensional NMR techniques into one-dimensional techniques using Gaussian pulses

  Journal of Magnetic Resonance (1969) · 1986 · 10.1016/0022-2364(86)90366-5

• Correlation of connected transitions by two-dimensional NMR spectroscopy

  The Journal of Chemical Physics · 1986 · 10.1063/1.451421

• Two-dimensional correlation of connected NMR transitions

  Journal of the American Chemical Society · 1985 · 10.1021/ja00308a042

• Assignment of carbonyl carbons and sequence analysis in peptides by heteronuclear shift correlation via small coupling constants with broadband decoupling in t1 (COLOC)

  Journal of Magnetic Resonance (1969) · 1984 · 10.1016/0022-2364(84)90136-7

Current projects

No projects listed.