Wendy R. Parulekar

Research interests

Publications

• Anthracycline-containing and taxane-containing chemotherapy for early-stage operable breast cancer: a patient-level meta-analysis of 100 000 women from 86 randomised trials

  The Lancet · 2023 · https://doi.org/10.1016/s0140-6736(23)00285-4

• Testosterone suppression plus enzalutamide versus testosterone suppression plus standard antiandrogen therapy for metastatic hormone-sensitive prostate cancer (ENZAMET): an international, open-label, randomised, phase 3 trial

  The Lancet Oncology · 2023 · https://doi.org/10.1016/s1470-2045(23)00063-3

• Mature Local Control and Reirradiation Rates Comparing Spine Stereotactic Body Radiation Therapy With Conventional Palliative External Beam Radiation Therapy

  International Journal of Radiation Oncology*Biology*Physics · 2022 · 10.1016/j.ijrobp.2022.05.043

• Effect of Metformin vs Placebo on Invasive Disease–Free Survival in Patients With Breast Cancer

  JAMA · 2022 · https://doi.org/10.1001/jama.2022.6147

• Stereotactic body radiotherapy versus conventional external beam radiotherapy in patients with painful spinal metastases: an open-label, multicentre, randomised, controlled, phase 2/3 trial

  The Lancet Oncology · 2021 · https://doi.org/10.1016/s1470-2045(21)00196-0

• Timing of radiotherapy after radical prostatectomy (RADICALS-RT): a randomised, controlled phase 3 trial

  The Lancet · 2020 · https://doi.org/10.1016/s0140-6736(20)31553-1

• Enzalutamide with Standard First-Line Therapy in Metastatic Prostate Cancer

  New England Journal of Medicine · 2019 · https://doi.org/10.1056/nejmoa1903835

• Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials

  The Lancet · 2019 · https://doi.org/10.1016/s0140-6736(18)33137-4

• Extending Aromatase-Inhibitor Adjuvant Therapy to 10 Years

  New England Journal of Medicine · 2016 · https://doi.org/10.1056/nejmoa1604700

• Regional Nodal Irradiation in Early-Stage Breast Cancer

  New England Journal of Medicine · 2015 · https://doi.org/10.1056/nejmoa1415340

• Final Report of the Intergroup Randomized Study of Combined Androgen-Deprivation Therapy Plus Radiotherapy Versus Androgen-Deprivation Therapy Alone in Locally Advanced Prostate Cancer

  Journal of Clinical Oncology · 2015 · https://doi.org/10.1200/jco.2014.57.7510

• SPIRIT 2013 Statement: defining standard protocol items for clinical trials.

  PubMed · 2015

• Lapatinib or Trastuzumab Plus Taxane Therapy for Human Epidermal Growth Factor Receptor 2–Positive Advanced Breast Cancer: Final Results of NCIC CTG MA.31

  Journal of Clinical Oncology · 2015 · https://doi.org/10.1200/jco.2014.56.9590

• Effect of Metformin vs Placebo on and Metabolic Factors in NCIC CTG MA.32

  JNCI Journal of the National Cancer Institute · 2015 · 10.1093/jnci/djv006

• SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials

  BMJ · 2013 · https://doi.org/10.1136/bmj.e7586

• SPIRIT 2013 Statement: Defining Standard Protocol Items for Clinical Trials

  Annals of Internal Medicine · 2013 · https://doi.org/10.7326/0003-4819-158-3-201302050-00583

• NCIC-CTG MA.20: An intergroup trial of regional nodal irradiation in early breast cancer.

  Journal of Clinical Oncology · 2011 · https://doi.org/10.1200/jco.2011.29.18_suppl.lba1003

• Combined androgen deprivation therapy and radiation therapy for locally advanced prostate cancer: a randomised, phase 3 trial

  The Lancet · 2011 · https://doi.org/10.1016/s0140-6736(11)61095-7

• Evaluation of metformin in early breast cancer: a modification of the traditional paradigm for clinical testing of anti-cancer agents

  Breast Cancer Research and Treatment · 2010 · 10.1007/s10549-010-1224-1

• Molecular predictors of outcome in a phase 3 study of gemcitabine and erlotinib therapy in patients with advanced pancreatic cancer

  Cancer · 2010 · 10.1002/cncr.25393

• Meta-Analysis of Phase II Cooperative Group Trials in Metastatic Stage IV Melanoma to Determine Progression-Free and Overall Survival Benchmarks for Future Phase II Trials

  Journal of Clinical Oncology · 2008 · https://doi.org/10.1200/jco.2007.12.7837

• Radiotherapy and androgen deprivation in combination after local surgery (RADICALS): A new Medical Research Council/National Cancer Institute of Canada phase III trial of adjuvant treatment after radical prostatectomy

  British Journal of Urology · 2007 · 10.1111/j.1464-410x.2007.06844.x

• Erlotinib Plus Gemcitabine Compared With Gemcitabine Alone in Patients With Advanced Pancreatic Cancer: A Phase III Trial of the National Cancer Institute of Canada Clinical Trials Group

  Journal of Clinical Oncology · 2007 · https://doi.org/10.1200/jco.2006.07.9525

• Influence of Sex on Toxicity and Treatment Outcome in Small-Cell Lung Cancer

  Journal of Clinical Oncology · 2005 · 10.1200/jco.2005.03.171

• Incidence and Prognostic Impact of Amenorrhea During Adjuvant Therapy in High-Risk Premenopausal Breast Cancer: Analysis of a National Cancer Institute of Canada Clinical Trials Group Study—NCIC CTG MA.5

  Journal of Clinical Oncology · 2005 · 10.1200/jco.2005.07.096

• Phase I Trial Design for Solid Tumor Studies of Targeted, Non-Cytotoxic Agents: Theory and Practice

  JNCI Journal of the National Cancer Institute · 2004 · https://doi.org/10.1093/jnci/djh182

• Randomized, Double-Blind, Controlled Trial of Mitoxantrone/Prednisone and Clodronate Versus Mitoxantrone/Prednisone and Placebo in Patients With Hormone-Refractory Prostate Cancer and Pain

  Journal of Clinical Oncology · 2003 · https://doi.org/10.1200/jco.2003.03.042

• Use of Small-Bore vs Large-Bore Chest Tubes for Treatment of Malignant Pleural Effusions

  CHEST Journal · 2001 · 10.1378/chest.120.1.19

• Scoring oral mucositis

  Oral Oncology · 1998 · 10.1016/s1368-8375(97)00065-1

Current projects

No projects listed.