Ronald J. A. Wanders

Research interests

Publications

• Systematic mapping of contact sites reveals tethers and a function for the peroxisome-mitochondria contact

  Nature Communications · 2018 · 10.1038/s41467-018-03957-8

• Disorders of mitochondrial long-chain fatty acid oxidation and the carnitine shuttle

  Reviews in Endocrine and Metabolic Disorders · 2018 · 10.1007/s11154-018-9448-1

• Metabolic Interplay between Peroxisomes and Other Subcellular Organelles Including Mitochondria and the Endoplasmic Reticulum

  Frontiers in Cell and Developmental Biology · 2016 · 10.3389/fcell.2015.00083

• Human disorders of peroxisome metabolism and biogenesis

  Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2015 · 10.1016/j.bbamcr.2015.11.015

• The Biochemistry and Physiology of Mitochondrial Fatty Acid β-Oxidation and Its Genetic Disorders

  Annual Review of Physiology · 2015 · https://doi.org/10.1146/annurev-physiol-021115-105045

• Rhabdomyolysis: Review of the literature

  Neuromuscular Disorders · 2014 · 10.1016/j.nmd.2014.05.005

• Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies

  Nature Medicine · 2014 · https://doi.org/10.1038/nm.3545

• X-linked adrenoleukodystrophy (X-ALD): clinical presentation and guidelines for diagnosis, follow-up and management

  Orphanet Journal of Rare Diseases · 2012 · 10.1186/1750-1172-7-51

• A general introduction to the biochemistry of mitochondrial fatty acid β‐oxidation

  Journal of Inherited Metabolic Disease · 2010 · https://doi.org/10.1007/s10545-010-9061-2

• The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways

  Endocrine Reviews · 2010 · https://doi.org/10.1210/er.2009-0026

• Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: A review

  Journal of Inherited Metabolic Disease · 2008 · 10.1007/s10545-008-0841-x

• Cardiolipin provides an essential activating platform for caspase-8 on mitochondria

  The Journal of Cell Biology · 2008 · https://doi.org/10.1083/jcb.200803129

• A Lethal Defect of Mitochondrial and Peroxisomal Fission

  New England Journal of Medicine · 2007 · 10.1056/nejmoa064436

• Biochemistry of Mammalian Peroxisomes Revisited

  Annual Review of Biochemistry · 2006 · https://doi.org/10.1146/annurev.biochem.74.082803.133329

• Functions and biosynthesis of plasmalogens in health and disease

  Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2004 · 10.1016/j.bbalip.2003.12.010

• Carnitine biosynthesis in mammals

  Biochemical Journal · 2002 · 10.1042/bj3610417

• Carnitine biosynthesis in mammals

  Biochemical Journal · 2002 · 10.1042/0264-6021:3610417

• Mutations in the 3β-Hydroxysterol Δ24-Reductase Gene Cause Desmosterolosis, an Autosomal Recessive Disorder of Cholesterol Biosynthesis

  The American Journal of Human Genetics · 2001 · 10.1086/323473

• ABCD1 mutations and the X-linked adrenoleukodystrophy mutation database: Role in diagnosis and clinical correlations

  Human Mutation · 2001 · 10.1002/humu.1227

• Defective Remodeling of Cardiolipin and Phosphatidylglycerol in Barth Syndrome

  Biochemical and Biophysical Research Communications · 2000 · 10.1006/bbrc.2000.3952

• Smith-Lemli-Opitz Syndrome Is Caused by Mutations in the 7-Dehydrocholesterol Reductase Gene

  The American Journal of Human Genetics · 1998 · 10.1086/301982

• Refsum disease is caused by mutations in the phytanoyl–CoA hydroxylase gene

  Nature Genetics · 1997 · 10.1038/ng1097-190

• The ABC transporter proteins Pat1 and Pat2 are required for import of long‐chain fatty acids into peroxisomes of Saccharomyces cerevisiae.

  The EMBO Journal · 1996 · 10.1002/j.1460-2075.1996.tb00755.x

• The membrane of peroxisomes in Saccharomyces cerevisiae is impermeable to NAD(H) and acetyl‐CoA under in vivo conditions.

  The EMBO Journal · 1995 · 10.1002/j.1460-2075.1995.tb07354.x

• Peroxisomal disorders: A newly recognised group of genetic diseases

  European Journal of Pediatrics · 1986 · 10.1007/bf00441734

Current projects

No projects listed.