Helmut Sies

Research interests

Publications

• Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology

  Nature Reviews Molecular Cell Biology · 2022 · https://doi.org/10.1038/s41580-022-00456-z

• Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

  Nature Reviews Molecular Cell Biology · 2020 · https://doi.org/10.1038/s41580-020-0230-3

• Oxidative Stress

  Annual Review of Biochemistry · 2017 · https://doi.org/10.1146/annurev-biochem-061516-045037

• Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress

  Redox Biology · 2017 · 10.1016/j.redox.2016.12.035

• Oxidative stress: a concept in redox biology and medicine

  Redox Biology · 2015 · https://doi.org/10.1016/j.redox.2015.01.002

• Role of Metabolic H2O2 Generation

  Journal of Biological Chemistry · 2014 · 10.1074/jbc.r113.544635

• (–)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans

  Proceedings of the National Academy of Sciences · 2006 · 10.1073/pnas.0510168103

• Bioactivity and protective effects of natural carotenoids

  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2004 · 10.1016/j.bbadis.2004.12.006

• Antioxidant activity of carotenoids

  Molecular Aspects of Medicine · 2003 · 10.1016/s0098-2997(03)00030-x

• Sulfur and Selenium: The Role of Oxidation State in Protein Structure and Function

  Angewandte Chemie International Edition · 2003 · 10.1002/anie.200300573

• Chemistry of Biologically Important Synthetic Organoselenium Compounds

  Chemical Reviews · 2001 · 10.1021/cr000426w

• Glutathione and its role in cellular functions

  Free Radical Biology and Medicine · 1999 · 10.1016/s0891-5849(99)00177-x

• Oxidative stress: oxidants and antioxidants

  Experimental Physiology · 1997 · https://doi.org/10.1113/expphysiol.1997.sp004024

• Lycopene: A Biologically Important Carotenoid for Humans?

  Archives of Biochemistry and Biophysics · 1996 · 10.1006/abbi.1996.0525

• Vitamins E and C, beta-carotene, and other carotenoids as antioxidants

  American Journal of Clinical Nutrition · 1995 · 10.1093/ajcn/62.6.1315s

• Strategies of antioxidant defense

  European Journal of Biochemistry · 1993 · 10.1111/j.1432-1033.1993.tb18025.x

• Antioxidant Functions of Vitamins

  Annals of the New York Academy of Sciences · 1992 · 10.1111/j.1749-6632.1992.tb17085.x

• Oxidative stress: From basic research to clinical application

  The American Journal of Medicine · 1991 · 10.1016/0002-9343(91)90281-2

• Antioxidant defense systems: the role of carotenoids, tocopherols, and thiols

  American Journal of Clinical Nutrition · 1991 · 10.1093/ajcn/53.1.194s

• Lycopene as the most efficient biological carotenoid singlet oxygen quencher

  Archives of Biochemistry and Biophysics · 1989 · 10.1016/0003-9861(89)90467-0

• Biochemistry of Oxidative Stress

  Angewandte Chemie International Edition in English · 1986 · 10.1002/anie.198610581

• Oxidative Stress: Introductory Remarks

  Elsevier eBooks · 1985 · 10.1016/b978-0-12-642760-8.50005-3

• A novel biologically active seleno-organic compound—1

  Biochemical Pharmacology · 1984 · 10.1016/0006-2952(84)90083-2

• [48] Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples

  Methods in enzymology on CD-ROM/Methods in enzymology · 1981 · 10.1016/s0076-6879(81)77050-2

• Hydroperoxide metabolism in mammalian organs.

  Physiological Reviews · 1979 · https://doi.org/10.1152/physrev.1979.59.3.527

Current projects

No projects listed.