Manuel Mayr

Research interests

Publications

• Effect of Alirocumab Added to High-Intensity Statin Therapy on Coronary Atherosclerosis in Patients With Acute Myocardial Infarction

  JAMA · 2022 · https://doi.org/10.1001/jama.2022.5218

• The ‘Digital Twin’ to enable the vision of precision cardiology

  European Heart Journal · 2020 · https://doi.org/10.1093/eurheartj/ehaa159

• Systems biology in cardiovascular disease: a multiomics approach

  Nature Reviews Cardiology · 2020 · 10.1038/s41569-020-00477-1

• Pkm2 Regulates Cardiomyocyte Cell Cycle and Promotes Cardiac Regeneration

  Circulation · 2020 · 10.1161/circulationaha.119.043067

• Towards Better Definition, Quantification and Treatment of Fibrosis in Heart Failure. A Scientific Roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology

  European Journal of Heart Failure · 2019 · 10.1002/ejhf.1406

• Higher spermidine intake is linked to lower mortality: a prospective population-based study

  American Journal of Clinical Nutrition · 2018 · https://doi.org/10.1093/ajcn/nqy102

• Mitochondria and ageing: role in heart, skeletal muscle and adipose tissue

  Journal of Cachexia Sarcopenia and Muscle · 2017 · 10.1002/jcsm.12178

• Circulating MicroRNA-122 Is Associated With the Risk of New-Onset Metabolic Syndrome and Type 2 Diabetes

  Diabetes · 2016 · https://doi.org/10.2337/db16-0731

• Cardioprotection and lifespan extension by the natural polyamine spermidine

  Nature Medicine · 2016 · https://doi.org/10.1038/nm.4222

• MicroRNAs in Cardiovascular Disease

  Journal of the American College of Cardiology · 2016 · 10.1016/j.jacc.2016.09.945

• Vascular Smooth Muscle Cell Calcification Is Mediated by Regulated Exosome Secretion

  Circulation Research · 2015 · 10.1161/circresaha.116.305012

• Cardiac fibroblast–derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy

  Journal of Clinical Investigation · 2014 · https://doi.org/10.1172/jci70577

• Discrimination and Net Reclassification of Cardiovascular Risk With Lipoprotein(a)

  Journal of the American College of Cardiology · 2014 · https://doi.org/10.1016/j.jacc.2014.03.061

• Lipidomics Profiling and Risk of Cardiovascular Disease in the Prospective Population-Based Bruneck Study

  Circulation · 2014 · 10.1161/circulationaha.113.002500

• Native T1 Mapping in Differentiation of Normal Myocardium From Diffuse Disease in Hypertrophic and Dilated Cardiomyopathy

  JACC. Cardiovascular imaging · 2013 · 10.1016/j.jcmg.2012.08.019

• Circulating MicroRNAs as Novel Biomarkers for Platelet Activation

  Circulation Research · 2013 · 10.1161/circresaha.111.300539

• Prospective Study on Circulating MicroRNAs and Risk of Myocardial Infarction

  Journal of the American College of Cardiology · 2012 · 10.1016/j.jacc.2012.03.056

• Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs

  Nature Cell Biology · 2012 · https://doi.org/10.1038/ncb2441

• Extracellular Matrix Composition and Remodeling in Human Abdominal Aortic Aneurysms: A Proteomics Approach

  Molecular & Cellular Proteomics · 2011 · 10.1074/mcp.m111.008128

• Calcium Regulates Key Components of Vascular Smooth Muscle Cell–Derived Matrix Vesicles to Enhance Mineralization

  Circulation Research · 2011 · 10.1161/circresaha.110.238808

• Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes

  Circulation Research · 2010 · 10.1161/circresaha.110.226357

• Proteomics Characterization of Extracellular Space Components in the Human Aorta

  Molecular & Cellular Proteomics · 2010 · 10.1074/mcp.m110.001693

• Oxidized Phospholipids, Lipoprotein(a), Lipoprotein-Associated Phospholipase A2 Activity, and 10-Year Cardiovascular Outcomes

  Arteriosclerosis Thrombosis and Vascular Biology · 2007 · https://doi.org/10.1161/atvbaha.107.145805

• Oxidized Phospholipids Predict the Presence and Progression of Carotid and Femoral Atherosclerosis and Symptomatic Cardiovascular Disease

  Journal of the American College of Cardiology · 2006 · https://doi.org/10.1016/j.jacc.2006.03.001

• Chronic Infections and the Risk of Carotid Atherosclerosis

  Circulation · 2001 · 10.1161/01.cir.103.8.1064

• Infections, Immunity, and Atherosclerosis

  Circulation · 2000 · 10.1161/01.cir.102.8.833

• Serum Soluble Heat Shock Protein 60 Is Elevated in Subjects With Atherosclerosis in a General Population

  Circulation · 2000 · 10.1161/01.cir.102.1.14

• Endothelial Cytotoxicity Mediated by Serum Antibodies to Heat Shock Proteins of Escherichia coli and Chlamydia pneumoniae

  Circulation · 1999 · 10.1161/01.cir.99.12.1560

• Myocardial metabolism of free fatty acids. Studies with 14C-labeled substrates in humans.

  Journal of Clinical Investigation · 1987 · 10.1172/jci112820

Current projects

No projects listed.