Patrice D. Cani

Research interests

Publications

• Gut microbiome and health: mechanistic insights

  Gut · 2022 · https://doi.org/10.1136/gutjnl-2021-326789

• Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms

  Nature Reviews Gastroenterology & Hepatology · 2022 · 10.1038/s41575-022-00631-9

• Novel insights into the genetically obese (ob/ob) and diabetic (db/db) mice: two sides of the same coin

  Microbiome · 2021 · https://doi.org/10.1186/s40168-021-01097-8

• Dysosmobacter welbionis is a newly isolated human commensal bacterium preventing diet-induced obesity and metabolic disorders in mice

  Gut · 2021 · https://doi.org/10.1136/gutjnl-2020-323778

• Gut Microbiota-Induced Changes in β-Hydroxybutyrate Metabolism Are Linked to Altered Sociability and Depression in Alcohol Use Disorder

  Cell Reports · 2020 · https://doi.org/10.1016/j.celrep.2020.108238

• Diet and depression: exploring the biological mechanisms of action

  Molecular Psychiatry · 2020 · https://doi.org/10.1038/s41380-020-00925-x

• Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study

  Nature Medicine · 2019 · https://doi.org/10.1038/s41591-019-0495-2

• Next-Generation Beneficial Microbes: The Case of Akkermansia muciniphila

  Frontiers in Microbiology · 2017 · 10.3389/fmicb.2017.01765

• Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

  Nature Reviews Gastroenterology & Hepatology · 2017 · https://doi.org/10.1038/nrgastro.2017.75

• A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

  Nature Medicine · 2016 · 10.1038/nm.4236

• Synbiotic approach restores intestinal homeostasis and prolongs survival in leukaemic mice with cachexia

  The ISME Journal · 2015 · https://doi.org/10.1038/ismej.2015.209

• Crosstalk between Gut Microbiota and Dietary Lipids Aggravates WAT Inflammation through TLR Signaling

  Cell Metabolism · 2015 · https://doi.org/10.1016/j.cmet.2015.07.026

• Towards a more comprehensive concept for prebiotics

  Nature Reviews Gastroenterology & Hepatology · 2015 · https://doi.org/10.1038/nrgastro.2015.47

• Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity

  Proceedings of the National Academy of Sciences · 2014 · 10.1073/pnas.1415174111

• Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

  Proceedings of the National Academy of Sciences · 2013 · https://doi.org/10.1073/pnas.1219451110

• Restoring Specific Lactobacilli Levels Decreases Inflammation and Muscle Atrophy Markers in an Acute Leukemia Mouse Model

  PLoS ONE · 2012 · https://doi.org/10.1371/journal.pone.0037971

• Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice

  Diabetes · 2011 · 10.2337/db11-0227

• Targeting gut microbiota in obesity: effects of prebiotics and probiotics

  Nature Reviews Endocrinology · 2011 · 10.1038/nrendo.2011.126

• Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

  Gut · 2009 · https://doi.org/10.1136/gut.2008.165886

• Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet–Induced Obesity and Diabetes in Mice

  Diabetes · 2008 · https://doi.org/10.2337/db07-1403

• Metabolic Endotoxemia Initiates Obesity and Insulin Resistance

  Diabetes · 2007 · https://doi.org/10.2337/db06-1491

Current projects

No projects listed.