Thomas Carroll

Research interests

Publications

• m6A RNA methylation impacts fate choices during skin morphogenesis

  eLife · 2020 · 10.7554/elife.56980

• Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria

  Cell · 2020 · 10.1016/j.cell.2020.10.046

• The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death

  Cell · 2019 · 10.1016/j.cell.2019.05.035

• Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons

  Nature Cell Biology · 2018 · https://doi.org/10.1038/s41556-018-0039-x

• WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids

  eLife · 2018 · 10.7554/elife.38279

• mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

  Nature Cell Biology · 2015 · https://doi.org/10.1038/ncb3225

• HES6 drives a critical AR transcriptional programme to induce castration‐resistant prostate cancer through activation of an E2F1‐mediated cell cycle network

  EMBO Molecular Medicine · 2014 · 10.1002/emmm.201303581

• Elevated levels of FOXA1 facilitate androgen receptor chromatin binding resulting in a CRPC-like phenotype

  Oncogene · 2013 · 10.1038/onc.2013.508

• Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B–cell differentiation

  Blood · 2013 · 10.1182/blood-2012-08-450114

• A complex secretory program orchestrated by the inflammasome controls paracrine senescence

  Nature Cell Biology · 2013 · https://doi.org/10.1038/ncb2784

• MicroRNA Regulation of Cbx7 Mediates a Switch of Polycomb Orthologs during ESC Differentiation

  Cell stem cell · 2012 · 10.1016/j.stem.2011.12.004

Current projects

No projects listed.