Andrew J. Macpherson

Research interests

Publications

• Microbiota-derived acetate enables the metabolic fitness of the brain innate immune system during health and disease

  Cell Metabolism · 2021 · 10.1016/j.cmet.2021.10.010

• Microbial network disturbances in relapsing refractory Crohn’s disease

  Nature Medicine · 2019 · 10.1038/s41591-018-0308-z

• Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks

  Proceedings of the National Academy of Sciences · 2018 · 10.1073/pnas.1720017115

• Environmental triggers in IBD: a review of progress and evidence

  Nature Reviews Gastroenterology & Hepatology · 2017 · https://doi.org/10.1038/nrgastro.2017.136

• Genome-guided design of a defined mouse microbiota that confers colonization resistance against Salmonella enterica serovar Typhimurium

  Nature Microbiology · 2016 · 10.1038/nmicrobiol.2016.215

• The maternal microbiota drives early postnatal innate immune development

  Science · 2016 · 10.1126/science.aad2571

• The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation

  Immunity · 2015 · 10.1016/j.immuni.2015.09.012

• The outer mucus layer hosts a distinct intestinal microbial niche

  Nature Communications · 2015 · 10.1038/ncomms9292

• The Liver May Act as a Firewall Mediating Mutualism Between the Host and Its Gut Commensal Microbiota

  Science Translational Medicine · 2014 · 10.1126/scitranslmed.3008618

• Sex Differences in the Gut Microbiome Drive Hormone-Dependent Regulation of Autoimmunity

  Science · 2013 · https://doi.org/10.1126/science.1233521

• Interactions Between the Microbiota and the Immune System

  Science · 2012 · https://doi.org/10.1126/science.1223490

• Intestinal Bacterial Colonization Induces Mutualistic Regulatory T Cell Responses

  Immunity · 2011 · 10.1016/j.immuni.2011.03.021

• Depletion of Murine Intestinal Microbiota: Effects on Gut Mucosa and Epithelial Gene Expression

  PLoS ONE · 2011 · 10.1371/journal.pone.0017996

• Immune adaptations that maintain homeostasis with the intestinal microbiota

  Nature reviews. Immunology · 2010 · https://doi.org/10.1038/nri2710

• Reversible Microbial Colonization of Germ-Free Mice Reveals the Dynamics of IgA Immune Responses

  Science · 2010 · 10.1126/science.1188454

• Like Will to Like: Abundances of Closely Related Species Can Predict Susceptibility to Intestinal Colonization by Pathogenic and Commensal Bacteria

  PLoS Pathogens · 2010 · 10.1371/journal.ppat.1000711

• Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism

  Science · 2009 · 10.1126/science.1172747

• The immune geography of IgA induction and function

  Mucosal Immunology · 2007 · https://doi.org/10.1038/mi.2007.6

• Salmonella enterica Serovar Typhimurium Exploits Inflammation to Compete with the Intestinal Microbiota

  PLoS Biology · 2007 · 10.1371/journal.pbio.0050244

• Use of axenic animals in studying the adaptation of mammals to their commensal intestinal microbiota

  Seminars in Immunology · 2006 · 10.1016/j.smim.2006.10.002

• Interactions between commensal intestinal bacteria and the immune system

  Nature reviews. Immunology · 2004 · https://doi.org/10.1038/nri1373

• Induction of Protective IgA by Intestinal Dendritic Cells Carrying Commensal Bacteria

  Science · 2004 · https://doi.org/10.1126/science.1091334

• A Primitive T Cell-Independent Mechanism of Intestinal Mucosal IgA Responses to Commensal Bacteria

  Science · 2000 · 10.1126/science.288.5474.2222

• Mucosal antibodies in inflammatory bowel disease are directed against intestinal bacteria.

  Gut · 1996 · 10.1136/gut.38.3.365

• Intestinal permeability: An overview

  Gastroenterology · 1995 · 10.1016/0016-5085(95)90708-4

Current projects

No projects listed.