Bing Lim

Research interests

Publications

• Genomic landscape of lung adenocarcinoma in East Asians

  Nature Genetics · 2020 · https://doi.org/10.1038/s41588-019-0569-6

• Methionine is a metabolic dependency of tumor-initiating cells

  Nature Medicine · 2019 · https://doi.org/10.1038/s41591-019-0423-5

• Correction: Corrigendum: Endothelin-1 supports clonal derivation and expansion of cardiovascular progenitors derived from human embryonic stem cells

  Nature Communications · 2016 · https://doi.org/10.1038/ncomms12118

• Efficient Endoderm Induction from Human Pluripotent Stem Cells by Logically Directing Signals Controlling Lineage Bifurcations

  Cell stem cell · 2014 · https://doi.org/10.1016/j.stem.2013.12.007

• Protein Kinase C α Is a Central Signaling Node and Therapeutic Target for Breast Cancer Stem Cells

  Cancer Cell · 2013 · https://doi.org/10.1016/j.ccr.2013.08.005

• Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis

  Cell · 2012 · https://doi.org/10.1016/j.cell.2011.11.050

• Distal Airway Stem Cells Yield Alveoli In Vitro and during Lung Regeneration following H1N1 Influenza Infection

  Cell · 2011 · https://doi.org/10.1016/j.cell.2011.10.001

• The Nuclear Receptor Nr5a2 Can Replace Oct4 in the Reprogramming of Murine Somatic Cells to Pluripotent Cells

  Cell stem cell · 2010 · https://doi.org/10.1016/j.stem.2009.12.009

• A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity

  Nature · 2010 · https://doi.org/10.1038/nature09531

• miR-200 Enhances Mouse Breast Cancer Cell Colonization to Form Distant Metastases

  PLoS ONE · 2009 · https://doi.org/10.1371/journal.pone.0007181

• MicroRNA-125b is a novel negative regulator of p53

  Genes & Development · 2009 · https://doi.org/10.1101/gad.1767609

• MicroRNAs Induced During Adipogenesis that Accelerate Fat Cell Development Are Downregulated in Obesity

  Diabetes · 2009 · https://doi.org/10.2337/db08-1299

• Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb

  Nature Cell Biology · 2009 · https://doi.org/10.1038/ncb1827

• Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells

  RNA · 2009 · https://doi.org/10.1261/rna.1441510

• MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation

  Nature · 2008 · https://doi.org/10.1038/nature07299

• Retinoic Acid Increases Foxp3+ Regulatory T Cells and Inhibits Development of Th17 Cells by Enhancing TGF-β-Driven Smad3 Signaling and Inhibiting IL-6 and IL-23 Receptor Expression

  The Journal of Immunology · 2008 · https://doi.org/10.4049/jimmunol.181.4.2277

• Identification of Common Pathways Mediating Differentiation of Bone Marrow- and Adipose Tissue-Derived Human Mesenchymal Stem Cells into Three Mesenchymal Lineages

  Stem Cells · 2006 · https://doi.org/10.1634/stemcells.2006-0394

• The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

  Nature Genetics · 2006 · https://doi.org/10.1038/ng1760

• Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1

  Nature Cell Biology · 2006 · https://doi.org/10.1038/ncb1481

• A Pattern-Based Method for the Identification of MicroRNA Binding Sites and Their Corresponding Heteroduplexes

  Cell · 2006 · https://doi.org/10.1016/j.cell.2006.07.031

• A Global Map of p53 Transcription-Factor Binding Sites in the Human Genome

  Cell · 2006 · https://doi.org/10.1016/j.cell.2005.10.043

• Reciprocal Transcriptional Regulation of Pou5f1 and Sox2 via the Oct4/Sox2 Complex in Embryonic Stem Cells

  Molecular and Cellular Biology · 2005 · https://doi.org/10.1128/mcb.25.14.6031-6046.2005

• Comment on " 'Stemness': Transcriptional Profiling of Embryonic and Adult Stem Cells" and "A Stem Cell Molecular Signature" (I)

  Science · 2003 · https://doi.org/10.1126/science.1086384

• Linking β-Catenin to Androgen-signaling Pathway

  Journal of Biological Chemistry · 2002 · https://doi.org/10.1074/jbc.m111962200

Current projects

No projects listed.