Sophie Duraffour

Research interests

Publications

• Predicting the evolution of the Lassa virus endemic area and population at risk over the next decades

  Nature Communications · 2022 · https://doi.org/10.1038/s41467-022-33112-3

• Limited specificity of commercially available SARS‐CoV‐2 IgG ELISAs in serum samples of African origin

  Tropical Medicine & International Health · 2021 · 10.1111/tmi.13569

• Resurgence of Ebola virus in 2021 in Guinea suggests a new paradigm for outbreaks

  Nature · 2021 · https://doi.org/10.1038/s41586-021-03901-9

• Lassa fever outcomes and prognostic factors in Nigeria (LASCOPE): a prospective cohort study

  The Lancet Global Health · 2021 · 10.1016/s2214-109x(20)30518-0

• Metagenomic sequencing at the epicenter of the Nigeria 2018 Lassa fever outbreak

  Science · 2019 · https://doi.org/10.1126/science.aau9343

• Virus genomes reveal factors that spread and sustained the Ebola epidemic

  Nature · 2017 · https://doi.org/10.1038/nature22040

• Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus

  Genome biology · 2017 · https://doi.org/10.1186/s13059-016-1137-3

• Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea

  PLoS Medicine · 2016 · https://doi.org/10.1371/journal.pmed.1001967

• Resurgence of Ebola Virus Disease in Guinea Linked to a Survivor With Virus Persistence in Seminal Fluid for More Than 500 Days

  Clinical Infectious Diseases · 2016 · https://doi.org/10.1093/cid/ciw601

• Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!)

  The Lancet · 2016 · https://doi.org/10.1016/s0140-6736(16)32621-6

• Unique human immune signature of Ebola virus disease in Guinea

  Nature · 2016 · https://doi.org/10.1038/nature17949

• Persistence and clearance of Ebola virus RNA from seminal fluid of Ebola virus disease survivors: a longitudinal analysis and modelling study

  The Lancet Global Health · 2016 · https://doi.org/10.1016/s2214-109x(16)30243-1

• Ebola Virus Persistence in Breast Milk After No Reported Illness: A Likely Source of Virus Transmission From Mother to Child

  Clinical Infectious Diseases · 2016 · 10.1093/cid/ciw793

• Real-time, portable genome sequencing for Ebola surveillance

  Nature · 2016 · https://doi.org/10.1038/nature16996

• Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial

  The Lancet · 2015 · https://doi.org/10.1016/s0140-6736(15)61117-5

• Temporal and spatial analysis of the 2014–2015 Ebola virus outbreak in West Africa

  Nature · 2015 · https://doi.org/10.1038/nature14594

• ST-246 is a key antiviral to inhibit the viral F13L phospholipase, one of the essential proteins for orthopoxvirus wrapping

  Journal of Antimicrobial Chemotherapy · 2015 · https://doi.org/10.1093/jac/dku545

• Vaccinia Virus–Encoded Ribonucleotide Reductase Subunits Are Differentially Required for Replication and Pathogenesis

  PLoS Pathogens · 2010 · 10.1371/journal.ppat.1000984

Current projects

No projects listed.