Kazuhiko Koike

Research interests

Publications

• Evidence-based clinical practice guidelines for inflammatory bowel disease 2020

  Journal of Gastroenterology · 2021 · https://doi.org/10.1007/s00535-021-01784-1

• Evidence-based clinical practice guidelines for Liver Cirrhosis 2020

  Journal of Gastroenterology · 2021 · https://doi.org/10.1007/s00535-021-01788-x

• Hepatocellular carcinoma

  Nature Reviews Disease Primers · 2021 · https://doi.org/10.1038/s41572-020-00240-3

• Tumor microenvironment in gastric cancers

  Cancer Science · 2020 · https://doi.org/10.1111/cas.14521

• Japan Gastroenterological Endoscopy Society guidelines for colorectal endoscopic submucosal dissection/endoscopic mucosal resection

  Digestive Endoscopy · 2019 · https://doi.org/10.1111/den.13545

• p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells

  Cancer Cell · 2016 · https://doi.org/10.1016/j.ccell.2016.04.006

• Nerve Growth Factor Promotes Gastric Tumorigenesis through Aberrant Cholinergic Signaling

  Cancer Cell · 2016 · https://doi.org/10.1016/j.ccell.2016.11.005

• Sarcopenia, intramuscular fat deposition, and visceral adiposity independently predict the outcomes of hepatocellular carcinoma

  Journal of Hepatology · 2015 · https://doi.org/10.1016/j.jhep.2015.02.031

• ER Stress Cooperates with Hypernutrition to Trigger TNF-Dependent Spontaneous HCC Development

  Cancer Cell · 2014 · https://doi.org/10.1016/j.ccr.2014.07.001

• The C-Reactive Protein/Albumin Ratio, a Novel Inflammation-Based Prognostic Score, Predicts Outcomes in Patients with Hepatocellular Carcinoma

  Annals of Surgical Oncology · 2014 · https://doi.org/10.1245/s10434-014-4048-0

• Daclatasvir plus asunaprevir for chronic HCV genotype 1b infection

  Hepatology · 2014 · https://doi.org/10.1002/hep.27113

• Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma

  Nature Genetics · 2014 · https://doi.org/10.1038/ng.2984

• Identification of Liver Cancer Progenitors Whose Malignant Progression Depends on Autocrine IL-6 Signaling

  Cell · 2013 · https://doi.org/10.1016/j.cell.2013.09.031

• Correction: Corrigendum: MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma

  Nature Communications · 2012 · https://doi.org/10.1038/ncomms2081

• Radiofrequency Ablation for Hepatocellular Carcinoma: 10-Year Outcome and Prognostic Factors

  The American Journal of Gastroenterology · 2011 · https://doi.org/10.1038/ajg.2011.425

• A systematic review of hepatitis C virus epidemiology in Asia, Australia and Egypt

  Liver International · 2011 · https://doi.org/10.1111/j.1478-3231.2011.02540.x

• Hepatocellular carcinoma with extrahepatic metastasis

  Cancer · 2011 · https://doi.org/10.1002/cncr.25960

• Characteristics of Patients With Nonalcoholic Steatohepatitis Who Develop Hepatocellular Carcinoma

  Clinical Gastroenterology and Hepatology · 2011 · https://doi.org/10.1016/j.cgh.2011.01.023

• Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma

  Nature Genetics · 2011 · https://doi.org/10.1038/ng.809

• Hepatitis C virus infection and diabetes: direct involvement of the virus in the development of insulin resistance

  Gastroenterology · 2004 · https://doi.org/10.1053/j.gastro.2003.11.056

• Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral‐related steatosis

  The FASEB Journal · 2002 · https://doi.org/10.1096/fj.01-0396com

• Oxidative stress in the absence of inflammation in a mouse model for hepatitis C virus-associated hepatocarcinogenesis.

  PubMed · 2001

• The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice

  Nature Medicine · 1998 · https://doi.org/10.1038/2053

• A Hecke Algebra of (Z/rZ)Sn and Construction of Its Irreducible Representations

  Advances in Mathematics · 1994 · https://doi.org/10.1006/aima.1994.1057

Current projects

No projects listed.