Giuseppe Penna

Research interests

Publications

• Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver

  Cancer Cell · 2021 · https://doi.org/10.1016/j.ccell.2021.03.004

• Identification of a choroid plexus vascular barrier closing during intestinal inflammation

  Science · 2021 · https://doi.org/10.1126/science.abc6108

• Endogenous murine microbiota member Faecalibaculum rodentium and its human homologue protect from intestinal tumour growth

  Nature Microbiology · 2020 · https://doi.org/10.1038/s41564-019-0649-5

• Microbiota-driven gut vascular barrier disruption is a prerequisite for non-alcoholic steatohepatitis development

  Journal of Hepatology · 2019 · https://doi.org/10.1016/j.jhep.2019.08.005

• The EGFR-specific antibody cetuximab combined with chemotherapy triggers immunogenic cell death

  Nature Medicine · 2016 · https://doi.org/10.1038/nm.4078

• Coagulation induced by C3aR-dependent NETosis drives protumorigenic neutrophils during small intestinal tumorigenesis

  Nature Communications · 2016 · https://doi.org/10.1038/ncomms11037

• BALB/c and C57BL/6 Mice Differ in Polyreactive IgA Abundance, which Impacts the Generation of Antigen-Specific IgA and Microbiota Diversity

  Immunity · 2015 · https://doi.org/10.1016/j.immuni.2015.08.011

• A gut-vascular barrier controls the systemic dissemination of bacteria

  Science · 2015 · https://doi.org/10.1126/science.aad0135

• Oral Tolerance Can Be Established via Gap Junction Transfer of Fed Antigens from CX3CR1+ Macrophages to CD103+ Dendritic Cells

  Immunity · 2014 · https://doi.org/10.1016/j.immuni.2013.12.012

• Probiotic and postbiotic activity in health and disease: comparison on a novel polarised ex-vivo organ culture model

  Gut · 2012 · https://doi.org/10.1136/gutjnl-2011-300971

• Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

  Gut · 2011 · https://doi.org/10.1136/gut.2010.212159

• Chronic inflammation in the pathogenesis of benign prostatic hyperplasia

  International Journal of Andrology · 2009 · https://doi.org/10.1111/j.1365-2605.2009.00972.x

• Seminal Plasma Cytokines and Chemokines in Prostate Inflammation: Interleukin 8 as a Predictive Biomarker in Chronic Prostatitis/Chronic Pelvic Pain Syndrome and Benign Prostatic Hyperplasia

  European Urology · 2006 · https://doi.org/10.1016/j.eururo.2006.07.016

• 1α,25-Dihydroxyvitamin D3 Inhibits Differentiation, Maturation, Activation, and Survival of Dendritic Cells Leading to Impaired Alloreactive T Cell Activation

  The Journal of Immunology · 2000 · https://doi.org/10.4049/jimmunol.164.5.2405

• Maturation Stages of Mouse Dendritic Cells in Growth Factor–dependent Long-Term Cultures

  The Journal of Experimental Medicine · 1997 · https://doi.org/10.1084/jem.185.2.317

Current projects

No projects listed.