Antonio Bertoletti

Research interests

Publications

• Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease

  Immunity · 2021 · https://doi.org/10.1016/j.immuni.2021.07.007

• Dynamics of SARS-CoV-2 neutralising antibody responses and duration of immunity: a longitudinal study

  The Lancet Microbe · 2021 · https://doi.org/10.1016/s2666-5247(21)00025-2

• Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients

  Cell Reports · 2021 · https://doi.org/10.1016/j.celrep.2021.108728

• Highly functional virus-specific cellular immune response in asymptomatic SARS-CoV-2 infection

  The Journal of Experimental Medicine · 2021 · https://doi.org/10.1084/jem.20202617

• SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls

  Nature · 2020 · https://doi.org/10.1038/s41586-020-2550-z

• Therapeutic strategies for hepatitis B virus infection: towards a cure

  Nature Reviews Drug Discovery · 2019 · 10.1038/s41573-019-0037-0

• Update of the statements on biology and clinical impact of occult hepatitis B virus infection

  Journal of Hepatology · 2019 · https://doi.org/10.1016/j.jhep.2019.03.034

• Adaptive immunity in HBV infection

  Journal of Hepatology · 2016 · 10.1016/j.jhep.2016.01.026

• Memory T cell responses targeting the SARS coronavirus persist up to 11 years post-infection

  Vaccine · 2016 · 10.1016/j.vaccine.2016.02.063

• HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant

  Gastroenterology · 2016 · 10.1053/j.gastro.2016.07.012

• Trained immunity in newborn infants of HBV-infected mothers

  Nature Communications · 2015 · https://doi.org/10.1038/ncomms7588

• IL-1β Production through the NLRP3 Inflammasome by Hepatic Macrophages Links Hepatitis C Virus Infection with Liver Inflammation and Disease

  PLoS Pathogens · 2013 · 10.1371/journal.ppat.1003330

• IL-7 Licenses Activation of Human Liver Intrasinusoidal Mucosal-Associated Invariant T Cells

  The Journal of Immunology · 2013 · 10.4049/jimmunol.1203218

• Human Tissues Contain CD141hi Cross-Presenting Dendritic Cells with Functional Homology to Mouse CD103+ Nonlymphoid Dendritic Cells

  Immunity · 2012 · https://doi.org/10.1016/j.immuni.2012.04.012

• Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection

  Gut · 2011 · 10.1136/gutjnl-2011-301073

• Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell–mediated liver damage

  The Journal of Experimental Medicine · 2007 · 10.1084/jem.20061287

• Characterization of Hepatitis B Virus (HBV)-Specific T-Cell Dysfunction in Chronic HBV Infection

  Journal of Virology · 2007 · https://doi.org/10.1128/jvi.02844-06

• The immune response during hepatitis B virus infection

  Journal of General Virology · 2006 · 10.1099/vir.0.81920-0

• Longitudinal Analysis of CD8+T Cells Specific for Structural and Nonstructural Hepatitis B Virus Proteins in Patients with Chronic Hepatitis B: Implications for Immunotherapy

  Journal of Virology · 2004 · 10.1128/jvi.78.11.5707-5719.2004

• The Role of Virus-Specific Cd8+ Cells in Liver Damage and Viral Control during Persistent Hepatitis B Virus Infection

  The Journal of Experimental Medicine · 2000 · https://doi.org/10.1084/jem.191.8.1269

• Incubation Phase of Acute Hepatitis B in Man: Dynamic of Cellular Immune Mechanisms

  Hepatology · 2000 · 10.1053/jhep.2000.19324

• Direct ex vivo analysis of hepatitis B virus-specific CD8+ T cells associated with the control of infection

  Gastroenterology · 1999 · 10.1016/s0016-5085(99)70289-1

• Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B.

  Journal of Clinical Investigation · 1998 · 10.1172/jci3731

• Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells

  Nature · 1994 · 10.1038/369407a0

• Cytotoxic T lymphocytes recognize an HLA-A2-restricted epitope within the hepatitis B virus nucleocapsid antigen.

  The Journal of Experimental Medicine · 1991 · 10.1084/jem.174.6.1565

• Cellular immune response to hepatitis B virus-encoded antigens in acute and chronic hepatitis B virus infection.

  The Journal of Immunology · 1990 · 10.4049/jimmunol.145.10.3442

Current projects

No projects listed.