Larry Rubinstein

Research interests

Publications

• Dabrafenib and Trametinib in Patients With Tumors With BRAF V600E Mutations: Results of the NCI-MATCH Trial Subprotocol H

  Journal of Clinical Oncology · 2020 · https://doi.org/10.1200/jco.20.00762

• Phase II Study of AZD4547 in Patients With Tumors Harboring Aberrations in the FGFR Pathway: Results From the NCI-MATCH Trial (EAY131) Subprotocol W

  Journal of Clinical Oncology · 2020 · https://doi.org/10.1200/jco.19.02630

• Molecular Landscape and Actionable Alterations in a Genomically Guided Cancer Clinical Trial: National Cancer Institute Molecular Analysis for Therapy Choice (NCI-MATCH)

  Journal of Clinical Oncology · 2020 · https://doi.org/10.1200/jco.19.03010

• The Molecular Analysis for Therapy Choice (NCI-MATCH) Trial: Lessons for Genomic Trial Design

  JNCI Journal of the National Cancer Institute · 2020 · https://doi.org/10.1093/jnci/djz245

• The National Cancer Institute ALMANAC: A Comprehensive Screening Resource for the Detection of Anticancer Drug Pairs with Enhanced Therapeutic Activity

  Cancer Research · 2017 · 10.1158/0008-5472.can-17-0489

• The National Cancer Institute ALMANAC: A Comprehensive Screening Resource for the Detection of Anticancer Drug Pairs with Enhanced Therapeutic Activity

  Cancer Research · 2017 · 10.1158/0008-5472.can-17-0489

• Clinical Trials in Recurrent Ovarian Cancer

  International Journal of Gynecological Cancer · 2011 · 10.1097/igc.0b013e31821bb8aa

• Clinical Trials in Recurrent Ovarian Cancer

  International Journal of Gynecological Cancer · 2011 · 10.1097/igc.0b013e31821bb8aa

• Phase I Study of PARP Inhibitor ABT-888 in Combination with Topotecan in Adults with Refractory Solid Tumors and Lymphomas

  Cancer Research · 2011 · 10.1158/0008-5472.can-11-1227

• Phase I Study of PARP Inhibitor ABT-888 in Combination with Topotecan in Adults with Refractory Solid Tumors and Lymphomas

  Cancer Research · 2011 · 10.1158/0008-5472.can-11-1227

• Phase 0 Clinical Trial of the Poly (ADP-Ribose) Polymerase Inhibitor ABT-888 in Patients With Advanced Malignancies

  Journal of Clinical Oncology · 2009 · 10.1200/jco.2008.19.7681

• Phase 0 Clinical Trial of the Poly (ADP-Ribose) Polymerase Inhibitor ABT-888 in Patients With Advanced Malignancies

  Journal of Clinical Oncology · 2009 · 10.1200/jco.2008.19.7681

• New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)

  European Journal of Cancer · 2008 · https://doi.org/10.1016/j.ejca.2008.10.026

• New guidelines to evaluate the response to treatment in solid tumors

  Breast Cancer · 2005 · 10.1007/bf02967383

• Risks and Benefits of Phase 1 Oncology Trials, 1991 through 2002

  New England Journal of Medicine · 2005 · 10.1056/nejmsa042220

• Design Issues of Randomized Phase II Trials and a Proposal for Phase II Screening Trials

  Journal of Clinical Oncology · 2005 · https://doi.org/10.1200/jco.2005.01.149

• New guidelines to evaluate the response to treatment in solid tumors

  Breast Cancer · 2005 · 10.1007/bf02967383

• Risks and Benefits of Phase 1 Oncology Trials, 1991 through 2002

  New England Journal of Medicine · 2005 · 10.1056/nejmsa042220

• Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials

  British Journal of Cancer · 2001 · 10.1054/bjoc.2001.1796

• Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials

  British Journal of Cancer · 2001 · 10.1054/bjoc.2001.1796

• New Guidelines to Evaluate the Response to Treatment in Solid Tumors

  JNCI Journal of the National Cancer Institute · 2000 · https://doi.org/10.1093/jnci/92.3.205

• Secondary Leukemia or Myelodysplastic Syndrome After Treatment With Epipodophyllotoxins

  Journal of Clinical Oncology · 1999 · 10.1200/jco.1999.17.2.569

• Secondary Leukemia or Myelodysplastic Syndrome After Treatment With Epipodophyllotoxins

  Journal of Clinical Oncology · 1999 · 10.1200/jco.1999.17.2.569

• Accelerated Titration Designs for Phase I Clinical Trials in Oncology

  JNCI Journal of the National Cancer Institute · 1997 · 10.1093/jnci/89.15.1138

• An Information-Intensive Approach to the Molecular Pharmacology of Cancer

  Science · 1997 · https://doi.org/10.1126/science.275.5298.343

• Accelerated Titration Designs for Phase I Clinical Trials in Oncology

  JNCI Journal of the National Cancer Institute · 1997 · 10.1093/jnci/89.15.1138

• Randomized trial of lobectomy versus limited resection for T1 N0 non-small cell lung cancer

  The Annals of Thoracic Surgery · 1995 · https://doi.org/10.1016/0003-4975(95)00537-u

• A comparison of two phase I trial designs

  Statistics in Medicine · 1994 · https://doi.org/10.1002/sim.4780131802

• Neural Computing in Cancer Drug Development: Predicting Mechanism of Action

  Science · 1992 · 10.1126/science.1411538

• Neural Computing in Cancer Drug Development: Predicting Mechanism of Action

  Science · 1992 · 10.1126/science.1411538

• Comparison of In Vitro Anticancer-Drug-Screening Data Generated With a Tetrazolium Assay Versus a Protein Assay Against a Diverse Panel of Human Tumor Cell Lines

  JNCI Journal of the National Cancer Institute · 1990 · 10.1093/jnci/82.13.1113

• Cancer recurrence after resection: T1 N0 non-small cell lung cancer

  The Annals of Thoracic Surgery · 1990 · 10.1016/0003-4975(90)90145-v

• Cancer recurrence after resection: T1 N0 non-small cell lung cancer

  The Annals of Thoracic Surgery · 1990 · 10.1016/0003-4975(90)90145-v

• Comparison of In Vitro Anticancer-Drug-Screening Data Generated With a Tetrazolium Assay Versus a Protein Assay Against a Diverse Panel of Human Tumor Cell Lines

  JNCI Journal of the National Cancer Institute · 1990 · 10.1093/jnci/82.13.1113

• Display and Analysis of Patterns of Differential Activity of Drugs Against Human Tumor Cell Lines: Development of Mean Graph and COMPARE Algorithm

  JNCI Journal of the National Cancer Institute · 1989 · https://doi.org/10.1093/jnci/81.14.1088

• Sites of recurrence in resected stage I non-small-cell lung cancer: a guide for future studies.

  Journal of Clinical Oncology · 1984 · 10.1200/jco.1984.2.12.1352

• Sites of recurrence in resected stage I non-small-cell lung cancer: a guide for future studies.

  Journal of Clinical Oncology · 1984 · 10.1200/jco.1984.2.12.1352

• Modern thirty-day operative mortality for surgical resections in lung cancer

  Journal of Thoracic and Cardiovascular Surgery · 1983 · 10.1016/s0022-5223(19)39080-4

• Modern thirty-day operative mortality for surgical resections in lung cancer

  Journal of Thoracic and Cardiovascular Surgery · 1983 · 10.1016/s0022-5223(19)39080-4

• Planning the duration of a comparative clinical trial with loss to follow-up and a period of continued observation

  Journal of Chronic Diseases · 1981 · 10.1016/0021-9681(81)90007-2

• Planning the duration of a comparative clinical trial with loss to follow-up and a period of continued observation

  Journal of Chronic Diseases · 1981 · 10.1016/0021-9681(81)90007-2

Current projects

No projects listed.