Francisca Vicente

Research interests

Publications

• Current Screening Methodologies in Drug Discovery for Selected Human Diseases

  Marine Drugs · 2018 · 10.3390/md16080279

• On line characterization of 58 phenolic compounds in Citrus fruit juices from Spanish cultivars by high-performance liquid chromatography with photodiode-array detection coupled to electrospray ionization triple quadrupole mass spectrometry

  Talanta · 2012 · 10.1016/j.talanta.2012.05.042

• A New Approach to Drug Discovery: High-Throughput Screening of Microbial Natural Extracts against Aspergillus fumigatus Using Resazurin

  SLAS DISCOVERY · 2012 · 10.1177/1087057111433459

• Discovery of Kibdelomycin, A Potent New Class of Bacterial Type II Topoisomerase Inhibitor by Chemical-Genetic Profiling in Staphylococcus aureus

  Chemistry & Biology · 2011 · 10.1016/j.chembiol.2011.06.011

• Current approaches to exploit actinomycetes as a source of novel natural products

  Journal of Industrial Microbiology & Biotechnology · 2010 · https://doi.org/10.1007/s10295-010-0882-7

• Overexpression of the trichodiene synthase gene tri5 increases trichodermin production and antimicrobial activity in Trichoderma brevicompactum

  Fungal Genetics and Biology · 2010 · 10.1016/j.fgb.2010.11.012

• A general analytical strategy for the characterization of phenolic compounds in fruit juices by high-performance liquid chromatography with diode array detection coupled to electrospray ionization and triple quadrupole mass spectrometry

  Journal of Chromatography A · 2009 · https://doi.org/10.1016/j.chroma.2009.05.039

• Enhancement of antibiotic and secondary metabolite detection from filamentous fungi by growth on nutritional arrays

  Journal of Applied Microbiology · 2008 · 10.1111/j.1365-2672.2008.03735.x

• Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties

  Proceedings of the National Academy of Sciences · 2007 · https://doi.org/10.1073/pnas.0700746104

• Isolation and Structure of Platencin: A FabH and FabF Dual Inhibitor with Potent Broad‐Spectrum Antibiotic Activity

  Angewandte Chemie International Edition · 2007 · https://doi.org/10.1002/anie.200701058

• Platensimycin is a selective FabF inhibitor with potent antibiotic properties

  Nature · 2006 · https://doi.org/10.1038/nature04784

• Isolation, Structure, and Absolute Stereochemistry of Platensimycin, A Broad Spectrum Antibiotic Discovered Using an Antisense Differential Sensitivity Strategy

  Journal of the American Chemical Society · 2006 · https://doi.org/10.1021/ja062232p

• Discovery of FabH/FabF Inhibitors from Natural Products

  Antimicrobial Agents and Chemotherapy · 2006 · https://doi.org/10.1128/aac.50.2.519-526.2006

• On-line characterisation of apple polyphenols by liquid chromatography coupled with mass spectrometry and ultraviolet absorbance detection

  Journal of Chromatography A · 2004 · 10.1016/j.chroma.2004.06.077

• Discovery of a Small Molecule That Inhibits Cell Division by Blocking FtsZ, a Novel Therapeutic Target of Antibiotics

  Journal of Biological Chemistry · 2003 · https://doi.org/10.1074/jbc.m307625200

• Pressurized liquid extraction for the determination of polyphenols in apple

  Journal of Chromatography A · 2001 · https://doi.org/10.1016/s0021-9673(01)01212-2

• Screening of antimicrobial activities in red, green and brown macroalgae from Gran Canaria (Canary Islands, Spain)

  International Microbiology · 2001 · https://doi.org/10.1007/s101230100006

• The Discovery of Enfumafungin, a Novel Antifungal Compound Produced by an Endophytic Hormonema Species Biological Activity and Taxonomy of the Producing Organisms

  Systematic and Applied Microbiology · 2000 · 10.1016/s0723-2020(00)80062-4

• Discovery of Novel Antifungal (1,3)-β- d -Glucan Synthase Inhibitors

  Antimicrobial Agents and Chemotherapy · 2000 · https://doi.org/10.1128/aac.44.2.368-377.2000

• Endophytic fungi from plants living on gypsum soils as a source of secondary metabolites with antimicrobial activity

  Mycological Research · 1998 · 10.1017/s0953756297005662

• A review of solid phase extraction: Basic principles and new developments

  Chromatographia · 1995 · https://doi.org/10.1007/bf02269916

Current projects

No projects listed.