Lawrence Steinman

Research interests

Publications

• Ublituximab versus Teriflunomide in Relapsing Multiple Sclerosis

  New England Journal of Medicine · 2022 · https://doi.org/10.1056/nejmoa2201904

• Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM

  Nature · 2022 · https://doi.org/10.1038/s41586-022-04432-7

• Safety and efficacy of ozanimod versus interferon beta-1a in relapsing multiple sclerosis (SUNBEAM): a multicentre, randomised, minimum 12-month, phase 3 trial

  The Lancet Neurology · 2019 · https://doi.org/10.1016/s1474-4422(19)30239-x

• Safety and efficacy of ozanimod versus interferon beta-1a in relapsing multiple sclerosis (RADIANCE): a multicentre, randomised, 24-month, phase 3 trial

  The Lancet Neurology · 2019 · https://doi.org/10.1016/s1474-4422(19)30238-8

• Treatment of Brain Inflammatory Diseases by Delivering Exosome Encapsulated Anti-inflammatory Drugs From the Nasal Region to the Brain

  Molecular Therapy · 2011 · https://doi.org/10.1038/mt.2011.164

• Common variants in P2RY11 are associated with narcolepsy

  Nature Genetics · 2010 · https://doi.org/10.1038/ng.734

• Phase 2 trial of a DNA vaccine encoding myelin basic protein for multiple sclerosis

  Annals of Neurology · 2008 · https://doi.org/10.1002/ana.21370

• Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein

  Nature Medicine · 2007 · https://doi.org/10.1038/nm1488

• Type II monocytes modulate T cell–mediated central nervous system autoimmune disease

  Nature Medicine · 2007 · https://doi.org/10.1038/nm1620

• A brief history of TH17, the first major revision in the TH1/TH2 hypothesis of T cell–mediated tissue damage

  Nature Medicine · 2007 · https://doi.org/10.1038/nm1551

• Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

  Nature Medicine · 2002 · https://doi.org/10.1038/nm0502-500

• The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters

  Proceedings of the National Academy of Sciences · 2000 · https://doi.org/10.1073/pnas.97.24.13003

• Induction of a non-encephalitogenic type 2 T helper-cell autoimmune response in multiple sclerosis after administration of an altered peptide ligand in a placebo-controlled, randomized phase II trial

  Nature Medicine · 2000 · https://doi.org/10.1038/80525

Current projects

No projects listed.