Hans Lassmann

Research interests

Publications

• Multiple Sclerosis Pathology

  Cold Spring Harbor Perspectives in Medicine · 2018 · 10.1101/cshperspect.a028936

• The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

  Immunity · 2017 · https://doi.org/10.1016/j.immuni.2017.08.008

• Loss of ‘homeostatic’ microglia and patterns of their activation in active multiple sclerosis

  Brain · 2017 · 10.1093/brain/awx113

• An updated histological classification system for multiple sclerosis lesions

  Acta Neuropathologica · 2016 · 10.1007/s00401-016-1653-y

• Clinical and pathological insights into the dynamic nature of the white matter multiple sclerosis plaque

  Annals of Neurology · 2015 · 10.1002/ana.24497

• Pathological mechanisms in progressive multiple sclerosis

  The Lancet Neurology · 2015 · 10.1016/s1474-4422(14)70256-x

• Immunopathology of autoantibody-associated encephalitides: clues for pathogenesis

  Brain · 2012 · https://doi.org/10.1093/brain/aws082

• Progressive multiple sclerosis: pathology and pathogenesis

  Nature Reviews Neurology · 2012 · 10.1038/nrneurol.2012.168

• Inflammatory Cortical Demyelination in Early Multiple Sclerosis

  New England Journal of Medicine · 2011 · https://doi.org/10.1056/nejmoa1100648

• Oxidative damage in multiple sclerosis lesions

  Brain · 2011 · 10.1093/brain/awr128

• The relation between inflammation and neurodegeneration in multiple sclerosis brains

  Brain · 2009 · https://doi.org/10.1093/brain/awp070

• MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47

  Brain · 2009 · https://doi.org/10.1093/brain/awp300

• Oligodendrocytes: biology and pathology

  Acta Neuropathologica · 2009 · 10.1007/s00401-009-0601-5

• The Immunopathology of Multiple Sclerosis: An Overview

  Brain Pathology · 2007 · https://doi.org/10.1111/j.1750-3639.2007.00064.x

• Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis

  Brain · 2007 · 10.1093/brain/awl371

• Remyelination is extensive in a subset of multiple sclerosis patients

  Brain · 2006 · 10.1093/brain/awl217

• Cortical demyelination and diffuse white matter injury in multiple sclerosis

  Brain · 2005 · https://doi.org/10.1093/brain/awh641

• Clonal Expansions of Cd8+ T Cells Dominate the T Cell Infiltrate in Active Multiple Sclerosis Lesions as Shown by Micromanipulation and Single Cell Polymerase Chain Reaction

  The Journal of Experimental Medicine · 2000 · 10.1084/jem.192.3.393

• Multiple Sclerosis and Chronic Autoimmune Encephalomyelitis

  American Journal Of Pathology · 2000 · 10.1016/s0002-9440(10)64537-3

• Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination

  Annals of Neurology · 2000 · https://doi.org/10.1002/1531-8249(200006)47:6<707::aid-ana3>3.0.co;2-q

• Activated Human T Cells, B Cells, and Monocytes Produce Brain-derived Neurotrophic Factor In Vitro and in Inflammatory Brain Lesions: A Neuroprotective Role of Inflammation?

  The Journal of Experimental Medicine · 1999 · 10.1084/jem.189.5.865

• Distinct Patterns of Multiple Sclerosis Pathology Indicates Heterogeneity in Pathogenesis

  Brain Pathology · 1996 · 10.1111/j.1750-3639.1996.tb00854.x

• Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques.

  PubMed · 1994

• Accumulation of abnormally phosphorylated τ precedes the formation of neurofibrillary tangles in Alzheimer's disease

  Brain Research · 1989 · 10.1016/0006-8993(89)91396-6

• Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein.

  PubMed · 1988

• Cellular immune reactivity within the CNS

  Trends in Neurosciences · 1986 · 10.1016/0166-2236(86)90077-9

Current projects

No projects listed.