Shigekazu Nagata

Research interests

Publications

• Apoptosis and Clearance of Apoptotic Cells

  Annual Review of Immunology · 2018 · 10.1146/annurev-immunol-042617-053010

• Calcium-dependent phospholipid scrambling by TMEM16F

  Nature · 2010 · 10.1038/nature09583

• Autoimmunity and the Clearance of Dead Cells

  Cell · 2010 · 10.1016/j.cell.2010.02.014

• Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

  Cell Death and Differentiation · 2009 · https://doi.org/10.1038/cdd.2009.44

• The Many Roles of FAS Receptor Signaling in the Immune System

  Immunity · 2009 · https://doi.org/10.1016/j.immuni.2009.01.001

• Identification of Tim4 as a phosphatidylserine receptor

  Nature · 2007 · https://doi.org/10.1038/nature06307

• Classification of cell death: recommendations of the Nomenclature Committee on Cell Death

  Cell Death and Differentiation · 2005 · 10.1038/sj.cdd.4401724

• Autoimmune Disease and Impaired Uptake of Apoptotic Cells in MFG-E8-Deficient Mice

  Science · 2004 · https://doi.org/10.1126/science.1094359

• Identification of a factor that links apoptotic cells to phagocytes

  Nature · 2002 · 10.1038/417182a

• Apoptotic DNA Fragmentation

  Experimental Cell Research · 2000 · 10.1006/excr.2000.4834

• Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

  Nature · 1998 · 10.1038/34214

• A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

  Nature · 1998 · https://doi.org/10.1038/34112

• Apoptosis by Death Factor

  Cell · 1997 · https://doi.org/10.1016/s0092-8674(00)81874-7

• Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis

  Nature · 1996 · 10.1038/380723a0

• The Fas Death Factor

  Science · 1995 · https://doi.org/10.1126/science.7533326

• Fas and Fas ligand: lpr and gld mutations

  Immunology Today · 1995 · 10.1016/0167-5699(95)80069-7

• Fas and Perforin Pathways as Major Mechanisms of T Cell-Mediated Cytotoxicity

  Science · 1994 · 10.1126/science.7518614

• Generalized lymphoproliferative disease in mice, caused by a point mutation in the fas ligand

  Cell · 1994 · 10.1016/0092-8674(94)90375-1

• A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen

  Journal of Biological Chemistry · 1993 · 10.1016/s0021-9258(18)82075-0

• Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family

  Cell · 1993 · 10.1016/0092-8674(93)90326-l

• Lethal effect of the anti-Fas antibody in mice

  Nature · 1993 · 10.1038/364806a0

• Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

  Nature · 1992 · https://doi.org/10.1038/356314a0

• The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen

  The Journal of Immunology · 1992 · 10.4049/jimmunol.148.4.1274

• The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

  Cell · 1991 · https://doi.org/10.1016/0092-8674(91)90614-5

• pEF-BOS, a powerful mammalian expression vector

  Nucleic Acids Research · 1990 · 10.1093/nar/18.17.5322

• Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor

  Nature · 1986 · 10.1038/319415a0

Current projects

No projects listed.