Paul Piehowski

Research interests

Publications

• Temporal dynamics of the multi-omic response to endurance exercise training

  Nature · 2024 · https://doi.org/10.1038/s41586-023-06877-w

• The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance

  Cancer Cell · 2021 · 10.1016/j.ccell.2021.06.003

• Tutorial: best practices and considerations for mass-spectrometry-based protein biomarker discovery and validation

  Nature Protocols · 2021 · https://doi.org/10.1038/s41596-021-00566-6

• Automated mass spectrometry imaging of over 2000 proteins from tissue sections at 100-μm spatial resolution

  Nature Communications · 2020 · https://doi.org/10.1038/s41467-019-13858-z

• Boosting to Amplify Signal with Isobaric Labeling (BASIL) Strategy for Comprehensive Quantitative Phosphoproteomic Characterization of Small Populations of Cells

  Analytical Chemistry · 2019 · https://doi.org/10.1021/acs.analchem.9b00024

• The human body at cellular resolution: the NIH Human Biomolecular Atlas Program

  Nature · 2019 · https://doi.org/10.1038/s41586-019-1629-x

• Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia

  Annals of Neurology · 2018 · https://doi.org/10.1002/ana.25266

• Nanodroplet processing platform for deep and quantitative proteome profiling of 10–100 mammalian cells

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-03367-w

• A transcriptomic atlas of aged human microglia

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-02926-5

• Spatially Resolved Proteome Mapping of Laser Capture Microdissected Tissue with Automated Sample Transfer to Nanodroplets

  Molecular & Cellular Proteomics · 2018 · 10.1074/mcp.tir118.000686

• Spatially Resolved Proteome Mapping of Laser Capture Microdissected Tissue with Automated Sample Transfer to Nanodroplets

  Molecular & Cellular Proteomics · 2018 · 10.1074/mcp.tir118.000686

• New mass spectrometry technologies contributing towards comprehensive and high throughput omics analyses of single cells

  The Analyst · 2018 · 10.1039/c8an01574k

• Informed-Proteomics: open-source software package for top-down proteomics

  Nature Methods · 2017 · 10.1038/nmeth.4388

• Spatially-Resolved Proteomics: Rapid Quantitative Analysis of Laser Capture Microdissected Alveolar Tissue Samples

  Scientific Reports · 2016 · 10.1038/srep39223

• Sources of Technical Variability in Quantitative LC–MS Proteomics: Human Brain Tissue Sample Analysis

  Journal of Proteome Research · 2013 · 10.1021/pr301146m

• Leucoagaricus gongylophorus Produces Diverse Enzymes for the Degradation of Recalcitrant Plant Polymers in Leaf-Cutter Ant Fungus Gardens

  Applied and Environmental Microbiology · 2013 · 10.1128/aem.03833-12

• Leucoagaricus gongylophorus Produces Diverse Enzymes for the Degradation of Recalcitrant Plant Polymers in Leaf-Cutter Ant Fungus Gardens

  Applied and Environmental Microbiology · 2013 · 10.1128/aem.03833-12

• Metagenomic and metaproteomic insights into bacterial communities in leaf-cutter ant fungus gardens

  The ISME Journal · 2012 · 10.1038/ismej.2012.10

• Metagenomic and metaproteomic insights into bacterial communities in leaf-cutter ant fungus gardens

  The ISME Journal · 2012 · 10.1038/ismej.2012.10

Current projects

No projects listed.