James Fulcher

Research interests

Publications

• Data for EMSL Project 60297 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2627055/3806714

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2625578/3807737

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2624693/3809056

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2625223/3807710

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2625361/3807728

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2625355/3807727

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2625404/3807730

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2624872/3809067

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2625195/3807706

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2624764/3809060

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2625831/3807744

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2625180/3807702

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2625103/3807697

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2625254/3807714

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2625287/3807721

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2625577/3807736

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2625264/3807716

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2625278/3807720

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2625187/3807704

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2625253/3807713

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2625581/3807740

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2624799/3809062

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2625218/3807707

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2624733/3809058

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2625832/3807745

• Data for EMSL Project 51846 from October 2022

  DOE Pacific Northwest National Laboratory (PNNL) Repository · 2026 · 10.25582/data.2022-10.2624809/3809063

• Discovery of Proteoforms Associated With Alzheimer's Disease Through Quantitative Top-Down Proteomics

  Molecular & Cellular Proteomics · 2025 · 10.1016/j.mcpro.2025.100983

• High-throughput Single-Cell Proteomics and Transcriptomics from the Same Cells with a Nanoliter-Scale Spin-Transfer Approach

  bioRxiv (Cold Spring Harbor Laboratory) · 2025 · 10.1101/2025.10.20.681067

• Characterization of Cytokine Treatment on Human Pancreatic Islets by Top‐Down Proteomics

  PROTEOMICS · 2025 · 10.1002/pmic.70044

• Spatial top-down proteomics for the functional characterization of human kidney

  Clinical Proteomics · 2025 · 10.1186/s12014-025-09531-x

• Single-cell proteomics of Arabidopsis leaf mesophyll identifies drought stress-related proteins

  bioRxiv (Cold Spring Harbor Laboratory) · 2024 · 10.1101/2024.07.01.601628

• Advances in mass spectrometry-enabled multiomics at single-cell resolution

  Current Opinion in Biotechnology · 2024 · 10.1016/j.copbio.2024.103096

• Parallel measurement of transcriptomes and proteomes from same single cells using nanodroplet splitting

  Nature Communications · 2024 · 10.1038/s41467-024-54099-z

• Single-cell proteomics of Arabidopsis leaf mesophyll identifies drought stress-related proteins

  bioRxiv (Cold Spring Harbor Laboratory) · 2024 · 10.1101/2024.07.01.601628

• Spatially Resolved Top-Down Proteomics of Tissue Sections Based on a Microfluidic Nanodroplet Sample Preparation Platform

  Molecular & Cellular Proteomics · 2023 · 10.1016/j.mcpro.2022.100491

• Deletion of Carboxypeptidase E in β-Cells Disrupts Proinsulin Processing but Does Not Lead to Spontaneous Development of Diabetes in Mice

  Diabetes · 2023 · 10.2337/db22-0945

• Evaluating Linear Ion Trap for MS3-Based Multiplexed Single-Cell Proteomics

  Analytical Chemistry · 2023 · 10.1021/acs.analchem.2c03739

• Neonatal NET-Inhibitory Factor improves survival in the cecal ligation and puncture model of polymicrobial sepsis by inhibiting neutrophil extracellular traps

  Frontiers in Immunology · 2023 · 10.3389/fimmu.2022.1046574

• TopPICR: A Companion R Package for Top-Down Proteomics Data Analysis

  Journal of Proteome Research · 2023 · 10.1021/acs.jproteome.2c00570

• IsoMatchMS : Open-Source Software for Automated Annotation and Visualization of High Resolution MALDI-MS Spectra

  Journal of the American Society for Mass Spectrometry · 2023 · 10.1021/jasms.3c00180

• Parallel measurement of transcriptomes and proteomes from same single cells using nanodroplet splitting

  bioRxiv (Cold Spring Harbor Laboratory) · 2022 · 10.1101/2022.05.17.492137

• Discovery top-down proteomics in symbiotic soybean root nodules

  Frontiers in Analytical Science · 2022 · 10.3389/frans.2022.1012707

• Enhancing Top-Down Proteomics of Brain Tissue with FAIMS

  Journal of Proteome Research · 2021 · 10.1021/acs.jproteome.1c00049

• Traceless Click-Assisted Native Chemical Ligation Enabled by Protecting Dibenzocyclooctyne from Acid-Mediated Rearrangement with Copper(I)

  Bioconjugate Chemistry · 2021 · 10.1021/acs.bioconjchem.1c00403

• Chemical synthesis of Shiga toxin subunit B using a next-generation traceless “helping hand” solubilizing tag

  Organic & Biomolecular Chemistry · 2019 · 10.1039/c9ob02012h

• Structure of Vps4 with circular peptides and implications for translocation of two polypeptide chains by AAA+ ATPases

  eLife · 2019 · 10.7554/elife.44071

• GFI1 functions in transcriptional control and cell fate determination require SNAG domain methylation to recruit LSD1

  Biochemical Journal · 2017 · 10.1042/bcj-2016-0558_cor

• A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription

  eLife · 2017 · 10.7554/elife.28723

• Neonatal NET-inhibitory factor and related peptides inhibit neutrophil extracellular trap formation

  Journal of Clinical Investigation · 2016 · 10.1172/jci83873

• GFI1 functions in transcriptional control and cell fate determination require SNAG domain methylation to recruit LSD1

  Biochemical Journal · 2016 · 10.1042/bcj20160558

• Pyraclostrobin Wash-off from Sugarcane Leaves and Aerobic Dissipation in Agricultural Soil

  Journal of Agricultural and Food Chemistry · 2014 · 10.1021/jf405506p

• Industrial Relations around the World: Labour Relations for Multinational Companies.

  Contemporary Sociology A Journal of Reviews · 1994 · 10.2307/2075192

Current projects

No projects listed.