Bobbie‐Jo Webb‐Robertson

Research interests

Publications

• Missing data in multi-omics integration: Recent advances through artificial intelligence

  Frontiers in Artificial Intelligence · 2023 · 10.3389/frai.2023.1098308

• Tutorial: best practices and considerations for mass-spectrometry-based protein biomarker discovery and validation

  Nature Protocols · 2021 · https://doi.org/10.1038/s41596-021-00566-6

• Automated mass spectrometry imaging of over 2000 proteins from tissue sections at 100-μm spatial resolution

  Nature Communications · 2020 · https://doi.org/10.1038/s41467-019-13858-z

• The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View

  Trends in cancer · 2020 · https://doi.org/10.1016/j.trecan.2020.01.004

• An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells

  Nature Communications · 2020 · 10.1038/s41467-020-16327-0

• Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention

  Cell Metabolism · 2020 · 10.1016/j.cmet.2019.12.005

• Better understanding and prediction of antiviral peptides through primary and secondary structure feature importance

  Scientific Reports · 2020 · 10.1038/s41598-020-76161-8

• The impact of proinflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes

  Nature Genetics · 2019 · 10.1038/s41588-019-0524-6

• MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape

  Proceedings of the National Academy of Sciences · 2018 · 10.1073/pnas.1706928115

• Biallelic Mutations in ATP5F1D, which Encodes a Subunit of ATP Synthase, Cause a Metabolic Disorder

  The American Journal of Human Genetics · 2018 · 10.1016/j.ajhg.2018.01.020

• Multi-platform ’Omics Analysis of Human Ebola Virus Disease Pathogenesis

  Cell Host & Microbe · 2017 · https://doi.org/10.1016/j.chom.2017.10.011

• Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development

  Drug Metabolism and Disposition · 2016 · 10.1124/dmd.115.068593

• MPLEx: a Robust and Universal Protocol for Single-Sample Integrative Proteomic, Metabolomic, and Lipidomic Analyses

  mSystems · 2016 · https://doi.org/10.1128/msystems.00043-16

• Review, Evaluation, and Discussion of the Challenges of Missing Value Imputation for Mass Spectrometry-Based Label-Free Global Proteomics

  Journal of Proteome Research · 2015 · https://doi.org/10.1021/pr501138h

• Pathogenic Influenza Viruses and Coronaviruses Utilize Similar and Contrasting Approaches To Control Interferon-Stimulated Gene Responses

  mBio · 2014 · https://doi.org/10.1128/mbio.01174-14

• Mechanisms of Severe Acute Respiratory Syndrome Coronavirus-Induced Acute Lung Injury

  mBio · 2013 · https://doi.org/10.1128/mbio.00271-13

• Release of Severe Acute Respiratory Syndrome Coronavirus Nuclear Import Block Enhances Host Transcription in Human Lung Cells

  Journal of Virology · 2013 · 10.1128/jvi.02520-12

• A Network Integration Approach to Predict Conserved Regulators Related to Pathogenicity of Influenza and SARS-CoV Respiratory Viruses

  PLoS ONE · 2013 · 10.1371/journal.pone.0069374

• Challenges in biomarker discovery: combining expert insights with statistical analysis of complex omics data

  Expert Opinion on Medical Diagnostics · 2012 · 10.1517/17530059.2012.718329

• A statistical selection strategy for normalization procedures in LC‐MS proteomics experiments through dataset‐dependent ranking of normalization scaling factors

  PROTEOMICS · 2011 · 10.1002/pmic.201100078

• Quantitative proteomics analysis of adsorbed plasma proteins classifies nanoparticles with different surface properties and size

  PROTEOMICS · 2011 · 10.1002/pmic.201100037

• Improved quality control processing of peptide-centric LC-MS proteomics data

  Bioinformatics · 2011 · 10.1093/bioinformatics/btr479

• Combined Statistical Analyses of Peptide Intensities and Peptide Occurrences Improves Identification of Significant Peptides from MS-Based Proteomics Data

  Journal of Proteome Research · 2010 · 10.1021/pr1005247

• Comparative Proteomics and Pulmonary Toxicity of Instilled Single-Walled Carbon Nanotubes, Crocidolite Asbestos, and Ultrafine Carbon Black in Mice

  Toxicological Sciences · 2010 · 10.1093/toxsci/kfq363

• Normalization Approaches for Removing Systematic Biases Associated with Mass Spectrometry and Label-Free Proteomics

  Journal of Proteome Research · 2006 · https://doi.org/10.1021/pr050300l

Current projects

No projects listed.