Youngki You

Research interests

Publications

• Challenges and Opportunities in State‐of‐the‐Art Proteomics Analysis for Biomarker Development From Plasma Extracellular Vesicles

  PROTEOMICS · 2025 · 10.1002/pmic.70036

• Protein carbamylation and proteomics: from artifacts to elucidation of biological functions

  Frontiers in Analytical Science · 2025 · 10.3389/frans.2024.1512573

• Exploring new frontiers in type 1 diabetes through advanced mass-spectrometry-based molecular measurements

  Trends in Molecular Medicine · 2024 · 10.1016/j.molmed.2024.07.009

• APOA2 increases cholesterol efflux capacity to plasma HDL by displacing the C-terminus of resident APOA1

  Journal of Lipid Research · 2024 · 10.1016/j.jlr.2024.100686

• Regulation of bacterial stringent response by an evolutionarily conserved ribosomal protein L11 methylation

  mBio · 2024 · 10.1128/mbio.01773-24

• Reduction of Chemokine CXCL9 Expression by Omega‐3 Fatty Acids via ADP‐Ribosylhydrolase ARH3 in MIN6 Insulin‐Producing Cells

  PROTEOMICS · 2024 · 10.1002/pmic.202400053

• Comparison of the ligand binding site of C1 domains: a molecular dynamics simulation study of the C1 domain–phorbol 13-acetate–membrane system

  Journal of Biomolecular Structure and Dynamics · 2023 · 10.1080/07391102.2022.2163699

• A proteomic meta-analysis refinement of plasma extracellular vesicles

  Scientific Data · 2023 · 10.1038/s41597-023-02748-1

• Analysis of a macrophage carbamylated proteome reveals a function in post-translational modification crosstalk

  Cell Communication and Signaling · 2023 · 10.1186/s12964-023-01257-3

• Probing the Diacylglycerol Binding Site of Presynaptic Munc13-1

  Biochemistry · 2021 · 10.1021/acs.biochem.1c00165

• Molecular dynamics simulation studies on binding of activator and inhibitor to Munc13-1 C1 in the presence of membrane

  Journal of Biomolecular Structure and Dynamics · 2021 · 10.1080/07391102.2021.2001375

• Modulation of proteasome activity by curcumin and didemethylcurcumin

  Journal of Biomolecular Structure and Dynamics · 2021 · 10.1080/07391102.2021.1911853

• Modulation of proteasome activity by curcumin and didemethylcurcumin

  bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 10.1101/2020.07.27.222679

• Effect of ethanol on Munc13‐1 C1 in Membrane: A Molecular Dynamics Simulation Study

  Alcoholism Clinical and Experimental Research · 2020 · 10.1111/acer.14363

• Munc13 Is a Molecular Target of Bryostatin 1

  Biochemistry · 2019 · 10.1021/acs.biochem.9b00427

• Structural determinants of phorbol ester binding activity of the C1a and C1b domains of protein kinase C theta

  Biochimica et Biophysica Acta (BBA) - Biomembranes · 2018 · 10.1016/j.bbamem.2018.01.007

• Resveratrol inhibits phorbol ester-induced membrane translocation of presynaptic Munc13-1

  Biochimica et Biophysica Acta (BBA) - General Subjects · 2017 · 10.1016/j.bbagen.2017.07.006

• Critical Role of Trp-588 of Presynaptic Munc13-1 for Ligand Binding and Membrane Translocation

  Biochemistry · 2017 · 10.1021/acs.biochem.7b00764

• Curcumin Inhibits Protein Kinase Cα Activity by Binding to Its C1 Domain

  Biochemistry · 2016 · 10.1021/acs.biochem.6b00932

• An Approach for a Substitution Matrix Based on Protein Blocks and Physicochemical Properties of Amino Acids through PCA

  Interdisciplinary Bio Central · 2014 · 10.4051/ibc.2014.6.4.0003

Current projects

No projects listed.